REU Site: Molecular and Biochemical Analysis of Proteins

该REU Site奖授予印第安纳州西拉斐特的普渡大学，将在2018-2020年夏季为8名学生提供为期10周的研究培训。该项目提供蛋白质功能分析方面的高级培训。它促进了对实验实验室研究的详细了解，对蛋白质生物化学的洞察，以及对更广泛的研究背景的欣赏。生物化学系教师指导的项目包括酶机制分析、翻译后蛋白质修饰、蛋白质组学和在广泛的生物学背景下研究的蛋白质-核酸相互作用，包括细胞周期控制、表观遗传基因调控和植物发育。为期三天的培训将介绍蛋白质生物化学和实验设计中的关键概念。该计划的其余部分将强调全日制研究，并辅之以每周一次的会议，内容涉及研究中的道德行为、专业交流和研究生院的申请过程。学生们将在系级研讨会和全校海报会议上展示他们的成果。该计划将招收生命科学和化学本科生，至少有四个学期的大学生活，并对研究感兴趣。参与者的选择将基于学术成绩、表现出的对研究的兴趣以及在生命科学领域具有杰出研究事业的潜力。预计共有24名学生，主要来自研究机会有限的学校，将在该计划中接受培训，并特别强调从生命科学中代表性不足的群体中招收学生。学生将学习研究是如何进行的，提高他们的科学交流技能，许多人将在科学会议上展示他们的工作成果。由生物基础设施部资助的所有REU网站项目使用的通用网络评估工具将用于确定培训计划的有效性。将对学生海报演示进行额外的评估。项目结束后，学生将被跟踪，以确定他们的职业道路，并将被要求回复通过NSF报告系统发送的自动电子邮件。欲了解更多信息，请访问http://www.ag.purdue.edu/biochem/Pages/REU.aspx，或联系国际组织(James Forney博士，电子邮件：forney@Purdue.edu)。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的学术价值和更广泛的影响审查标准进行评估，被认为值得支持。

This REU Site award to Purdue University in West Lafayette, Indiana, will provide research training for eight students for ten weeks during the summers of 2018- 2020. The program provides advanced training in the analysis of protein function. It facilitates detailed understanding of experimental laboratory research, insights into protein biochemistry and appreciation for the broader context of research. Projects mentored by faculty in the Department of Biochemistry include analysis of enzyme mechanisms, post-translational protein modifications, proteomics, and protein-nucleic acid interactions studied in a wide range of biological contexts including cell cycle control, epigenetic gene regulation and plant development. A three-day orientation will introduce key concepts in protein biochemistry and experimental design. The remainder of the program will emphasize full-time research supplemented with weekly sessions on ethical conduct in research, professional communication and the graduate school application process. Students will present their results at a departmental symposium and a university-wide poster session. The program will recruit life science and chemistry undergraduates with at least four semesters of college who have an interest in research. Selection of participants will be based on academic performance, demonstrated interest in research, and the potential for outstanding research careers in the life sciences. It is anticipated that a total of 24 students, primarily from schools with limited research opportunities, will be trained in the program with additional emphasis on recruiting students from groups that are underrepresented in the life sciences. Students will learn how research is conducted, improve their scientific communication skills and many will present the results of their work at scientific conferences.A common web-based assessment tool used by all REU Site programs funded by the Division of Biological Infrastructure will be used to determine the effectiveness of the training program. Additional assessments on student poster presentations will be performed. Students will be tracked after the program in order to determine their career paths and will be asked to respond to an automatic email sent via the NSF reporting system. More information is available by visiting http://www.ag.purdue.edu/biochem/Pages/REU.aspx, or by contacting the PI (Dr. James Forney at forney@purdue.edu).This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.