MRI: Acquisition of a Dual-Source Single-Crystal X-ray Diffractomter

该奖项由重大研究仪器和化学仪器项目支持。南达科他大学的安德鲁·赛克斯教授及其同事孙浩然和王振强正在购买一台双源单晶衍射仪。通常，X射线衍射仪可以准确和精确地测量分子的完整三维结构，包括键距离和角度，并提供关于分子相对于邻近分子的空间排列的准确信息。这里描述的研究影响到许多领域，包括有机化学和无机化学、材料化学和生物化学。该仪器是该学院和其他合作机构在化学和生物化学方面的本科生和研究生的教学以及研究和研究培训的组成部分。因为这是该州唯一的衍射设施，它是一种地区性资源。衍射仪还可以通过本科生研究经验(REU)计划，在地区大学和部落学校对与其有长期合作关系的本科生进行培训。该仪器还被广泛用于教育和培训代表不足的学生，如来自内布拉斯加州印第安人社区学院(NICC，位于南苏城，梅西和内华达州桑蒂)的美国原住民学生，他们参加了USD暑期研究。该奖项旨在加强各级研究和教育。这对于研究甾体的绝对结构和分析具有潜在生物医学应用的无机近红外活性染料特别有用。衍射仪也被用来确定用于碳氟催化的两亲(类洗涤剂)分子的结构。该仪器可用于阴离子传感器、荧光压力传感器和蒽醌亚胺阳离子荧光传感器的研究。它还被用来表征全氟烷基化过渡金属络合物和金属-有机超容器。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

This award is supported by the Major Research Instrumentation and the Chemical Instrumentation Programs. Professor Andrew Sykes from the University of South Dakota (USD) and colleagues Haoran Sun and Zhenqiang Wang are acquiring a dual-source single-crystal diffractometer. In general, an X-ray diffractometer allows accurate and precise measurements of the full three-dimensional structure of a molecule, including bond distances and angles, and provides accurate information about the spatial arrangement of a molecule relative to neighboring molecules. The studies described here impact many areas, including organic and inorganic chemistry, materials chemistry and biochemistry. This instrument is an integral part of teaching as well as research and research training of undergraduate and graduate students in chemistry and biochemistry at this and other collaborating institutions. Because this is the only diffraction facility in the state it serves as a regional resource. The diffractometer also enables training of undergraduates at regional colleges and tribal schools with whom the home institution has long-established relationships through Research Experiences for Undergraduates (REU) programs. The instrument is also used extensively in the education and training of underrepresented students such as Native American students from Nebraska Indian Community College (NICC, in South Sioux City, Macy and Santee, NE) who participate in summer research at USD.The award is aimed at enhancing research and education at all levels. It is especially useful for studying the absolute structure of steroids and for analyzing inorganic near-infrared active dyes with potential biomedical applications. The diffractometer is also employed to determine the structure of amphiphilic (detergent-like) molecules used in carbon-fluorine catalysis. The instrument is utilized in studies of anion sensors, fluorescent pressure sensors and anthraquinone-imine cation fluorescent sensors. It is also employed to characterize perfluoroalkylated transition metal complexes and metal-organic supercontainers.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.