MRI: Acquisition of High-Throughput Fluorescence Imaging System for Undergraduate Research and Teaching at Pace University

佩斯大学获得了一项自动高分辨率成像系统，用于筛选大量荧光斑马鱼幼体和癌细胞。这一自动化成像系统将极大地加强佩斯大学的科学研究。除了被佩斯大学的研究人员使用外，成像系统还将被整合到攻读高级生物和化学课程的本科生的科学培训中。这些课程的学生将获得实践研究经验，并在处理他们将收集的大型数据集时提高他们的定量和分析技能。在教学实验室中使用该系统将使我们能够在高水平的生物学课堂上进行基于探究的项目，让更多的学生接触到真正的科学实验和发现。自动化高分辨率荧光成像系统将用于解决神经科学、发育生物学、癌症生物学和生物物理化学领域的广泛重要问题。此外，这个成像系统将促进和促进生物系和化学系之间的跨部门研究合作，并吸引本科生参与可发表的研究。这个成像系统将允许教职员工和学生确定不同的基因如何影响神经回路，识别控制感觉器官发育和再生的关键基因，检查细胞增殖，并研究其他课题。利用该成像系统获得的研究结果将通过科学会议分享并发表在同行评议的期刊上。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

An award is made to Pace University to acquire an automated high-resolution imaging system for screening large numbers of fluorescent zebrafish larvae and cancer cells. This automated imaging system will dramatically enhance scientific research at Pace University. Beyond being used by researchers at Pace University, the imaging system will also be integrated into the scientific training of undergraduate students enrolled in upper-division Biology and Chemistry courses. Students in these courses will gain hands-on research experiences and improve their quantitative and analytical skills as they work through the large datasets that they will collect. The use of the system in teaching laboratories will allow us to pursue inquiry-based projects within upper-level biology classes, exposing many more students to authentic scientific experimentation and discovery. The automated high-resolution fluorescence imaging system will be used to tackle a broad range of important questions from the fields of neuroscience, developmental biology, cancer biology, and biophysical chemistry. Furthermore, this imaging system will facilitate and promote interdepartmental research collaborations between the Biology and Chemistry departments, and engage undergraduates in publishable research. This imaging system will allow faculty and students to determine how various genes impact neural circuits, to identify key genes governing sensory organ development and regeneration, to examine cell proliferations, and to work on other topics. The results from the research obtained with this imaging system will be shared via scientific meetings and published in peer-reviewed journals.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.