MRI: Acquisition of a Variable Temperature (3.8-300 K) X-Band Electron Paramagnetic Resonance Spectrometer

该奖项得到了主要研究仪器和化学研究仪器计划的支持。来自奥克兰大学的Roman Dembinski教授及其同事Xiangqun Zeng，Ferman Chavez，Wei Zhang和Amitava Adhikary正在获得一种可变温度，连续波X波段电子顺磁共振（EPR）光谱仪。一般来说，EPR光谱仪产生分子和固态材料的几何和电子结构的详细信息。它还用于获得有关自由基寿命的信息，这些自由基是参与有价值的化学转化以及可能的病理性生长起始的短寿命、高反应性物种。这些研究影响了多个领域，从无机和有机分子的合成到新固态材料的开发，再到具有磁性和生物学意义的化合物。雇用的例子从正在进行的研究中得到启发，该仪器是在奥克兰大学本科和研究生水平的研究和教学的一个组成部分。此外，研究人员正在与该地区许多感兴趣的用户共享光谱仪。该仪器加强了该机构在化学，生物化学和环境科学方面的教育使命，涉及密歇根州东南部广泛的种族和文化背景的学生。 学生用户包括底特律大都市地区的社会经济弱势群体和少数民族学生。授予该光谱仪的目的是加强各级的研究和教育。仪器采集在理解涉及对生物分子的自由基损伤及其修复和/或恢复的反应机制方面特别有用。该仪器还用于研究金属肽在活性氧形成中的作用，以及用于材料科学的铁磁耦合系统的研究。该仪器服务于研究溶解在离子液体中的分子中自由基介导的氧化还原过程的研究人员，以及那些试图了解超氧阴离子自由基等自由基与人类白内障成熟开始相关的作用的研究人员。该奖项反映了NSF的法定使命，通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

This award is supported by the Major Research Instrumentation and the Chemistry Research Instrumentation Programs. Professor Roman Dembinski from Oakland University and colleagues Xiangqun Zeng, Ferman Chavez, Wei Zhang and Amitava Adhikary are acquiring a variable-temperature, continuous-wave-X-band-electron paramagnetic resonance (EPR) spectrometer. In general, an EPR spectrometer yields detailed information on the geometric and electronic structure of molecular and solid-state materials. It is also used to obtain information about the lifetimes of free radicals, short-lived, highly reactive species involved in valuable chemical transformations as well as the initiation of possible pathological growth. These studies impact several areas, from the synthesis of inorganic and organic molecules to the development of new solid-state materials to compounds of magnetic and biological interest. Employing examples inspired from ongoing research, this instrument is an integral part of research and teaching at the undergraduate and graduate levels at Oakland University. Additionally, the investigators are sharing the spectrometer with many interested users from the area. The instrumentation strengthens the institution's educational mission in the chemical, biochemical, and environmental sciences, which involves students from a broad range of ethnic and cultural backgrounds in southeastern Michigan. The student users include socio-economically disadvantaged and minority students in the Detroit metropolitan area.The award of this spectrometer is aimed at enhancing research and education at all levels. The instrument acquisition is especially useful in understanding the mechanisms of reactions involving free radical damage to biomolecules and its repair and/or restitution. The instrument is also employed in investigations of the roles of metallo-peptides involved in reactive oxygen species formation and in research of feromagnetic-coupled systems for materials science. The instrumentation serves researchers studying free-radical-mediated redox processes in molecules dissolved in ionic liquids, and those trying to understand the role of free radicals such as superoxide anion radical that are related to the onset of maturity of human cataracts.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.