NSF Center for Synthetic Organic Electrochemistry

这个中心实现了合成化学家长期持有的目标：在氧化反应(去除电子)或还原反应(添加电子)中使用电子作为化学试剂。目前只有极少数情况下，这是可行的在有用的规模和一系列的底物。CSOE团队汇集了合成化学家、表面化学家、电分析化学家、理论家、材料科学家和化学工程师，以了解特定电极上发生的详细表面过程，并开发创造性的新化学反应。该中心开发的发现、新方法和技术使学术界和工业界都能够更安全和可持续地使用合成有机化学。其他更广泛的影响包括团队科学和创业方面的研究生和博士后培训，以及向包括难民社区在内的未得到充分服务的受众开展外联工作。美国国家科学基金会合成有机电化学中心(CSOE)的使命是通过发明能够实现的、绿色、安全和经济的新反应和揭开基本电化学反应的神秘面纱，使合成有机电化学成为主流。氧化和还原仍然使用大量的氧化剂和还原剂，而不是更环保和更有效的电化学方法。然而，随着合成有机化学家致力于更可持续的化学，制备电化学方法因其高生产效率、温和的条件和易于扩展而成为自然的选择。整合许多领域(电化学、材料科学、表面科学、计算建模、机械分析和合成有机化学)的专业知识，建立知识库、技术和仪器，以促进制备电化学方法的广泛采用。这个中心有四个冲刺。第一推力开发用于C-H官能化的电催化剂和介体。第二个推力是开发氧化电合成技术。第三个重点是还原电合成的方法和材料。第四个重点是将新的电合成方法应用于复杂有机合成。CSOE还根据合成有机化学家的需要设计仪器和电化学池。综合和协同的研究环境为研究生和博士后研究人员提供了独特的机会。通过与业界的积极合作伙伴关系，与不同的科学家和工程师的合作培训，以及参与社区范围的教育和外展，这种培训得到了进一步的加强。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

This center realizes a long-held goal of synthetic chemists: to use electrons as chemical reagents in oxidation reactions (removing electrons) or reduction reactions (adding electrons). There are currently very few cases where this is viable at useful scales and across a range of substrates. The CSOE team brings together synthetic chemists, surface chemists, electroanalytical chemists, theorists, materials scientists and chemical engineers to understand the detailed surface processes happening on a particular electrode and develop creative new chemical reactions. The discoveries, new methodologies and techniques developed in the Center enable safer and sustainable synthetic organic chemistry in both academia and industry. Other broader impacts include graduate and postdoctoral training in team science and entrepreneurship and outreach efforts to underserved audiences including refugee communities. The mission of the NSF Center for Synthetic Organic Electrochemistry (CSOE) is to make synthetic organic electrochemistry mainstream through the invention of enabling, green, safe, and economic new reactions and the demystification of fundamental electrochemical reactivity. Oxidations and reductions are still done with large amounts of oxidizing and reducing agents rather than the greener and more efficient electrochemical methodologies. However, as synthetic organic chemists work toward more sustainable chemistry, preparative electrochemical methods become natural choices due to their high product efficiency, mild conditions, and ease of scalability. Integrating expertise across many areas (electrochemistry, material science, surface science, computational modeling, mechanistic analysis, and synthetic organic chemistry) builds the knowledge base, techniques, and instrumentation to promote widespread adoption of preparative electrochemical methods. This Center has four thrusts. The first thrust develops electrocatalysts and mediators for C-H functionalization. The second thrust develops techniques for oxidative electrosynthesis. The third thrust focuses on methods and materials for reductive electrosynthesis. The fourth thrust applies the new electrosynthesis methods to complex organic synthesis. CSOE also designs instrumentation and electrochemical cells tailored to the needs of the synthetic organic chemist. The integrated and synergistic research environment offers unique opportunities for graduate students and postdoctoral researchers. This training is further enhanced through vibrant partnerships with industry, collaborative training with a diverse set of scientists and engineers, and by engaging in community-wide education and outreach.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.