MRI: Acquisition of a 400 MHz NMR spectrometer for undergraduate research and teaching in chemistry

该奖项由主要研究仪器项目和化学研究仪器项目支持。西方学院正在购买一台配备自动换样器的400 MHz核磁共振(核磁共振)光谱仪，以支持杰弗里·坎农、迈克尔·希尔、安德鲁·乌迪特、劳尔·纳瓦罗、伊曼纽尔·德斯帕内特-阿尤布教授和其他同事。这种光谱仪允许在各种领域进行研究，例如那些加速具有重大经济意义的化学反应的领域，以及允许研究具有生物相关性的物种。总体而言，核磁共振波谱是化学家用于阐明分子结构的最强大的工具之一。它被用来识别未知物质，表征分子中原子的特定排列，并研究分子在溶液或固体中相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱仪是必不可少的。该仪器是该学院和附近其他机构化学和生物化学专业本科生的教学和科研培训的组成部分。核磁共振光谱仪的获奖旨在加强各级的研究和教育。特别是对碳-碳键形成合成方法的探索和金属氧涂层碳电极上电催化碳氢键氧化的研究产生了重要影响。该仪器还用于探索从能量储存到聚合物合成的各种项目。此外，它还有助于研究天然产物合成中的芳烃脱芳烃反应。该光谱仪还被用于研究展示在多价噬菌体上的硫酸盐配体的肝素类抗凝血剂活性。这一奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

This award is supported by the Major Research Instrumentation and the Chemistry Research Instrumentation programs. Occidental College is acquiring a 400 MHz nuclear magnetic resonance (NMR) spectrometer equipped with a automatic sample changer to support Professors Jeffrey Cannon, Michael Hill, Andrew Udit, Raul Navarro, Emmanuelle Despagnet-Ayoub and other colleagues. This spectrometer allows research in a variety of fields such as those that accelerate chemical reactions of significant economic importance, as well as permitting study of biologically relevant species. In general, NMR spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution or in the solid state. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. This instrument is an integral part of teaching as well as research and research training of undergraduate students in chemistry and biochemistry at this college and other nearby institutions. The award of the NMR spectrometer is aimed at enhancing research and education at all levels. It especially impacts the exploration of synthetic methods for carbon-carbon bond formation and the studies of electrocatalytic carbon-hydrogen bond oxidation at metal-oxo-coated carbon electrodes. The instrumentation is also used for exploring projects varying from energy storage to polymer synthesis. In addition, it benefits investigations of arene dearomatization reactions for natural product synthesis. The spectrometer is also utilized in studies of sulfated ligands displayed on polyvalent bacteriophage for heparin-like anticoagulant activity.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.