Total Synthesis and Biological Evaluation of Australian Sponge Metabolites

澳大利亚天然产物和某些具有生态和治疗意义的类似物的功能合成的开发将会出现。这类活动将有助于确定和评估在管理海洋环境方面有价值的分子实体，减少从澳大利亚国内外海洋环境中清除生物的需要，并有助于维持和加强该国的化学合成能力。拟议的研究可能导致查明大堡礁生物产生的相关天然产品，并可能显示出更强大的活动和/或互补的生态作用。

The development of functional syntheses of Australian natural products and certain analogues of ecological and therapeutic significance will emerge. Such activities will lead to the identification and evaluation of molecular entities of value in managing marine environments, reduce the need for removal of organisms from marine environments both within and outside of Australia as well as helping maintain and enhance chemical synthesis capacity within the country. The proposed studies could lead to the identification of related natural products produced by organisms on the Great Barrier Reef and that may display even more potent activities and/or complementary ecological roles.