Synergistic Photocatalysis with short-lived intermediates in microfluidic systems

该项目的重点是在经典的流动或微芯片反应系统中进行光化学和/或光催化流动合成。在这种情况下，光氧化还原催化反应与不稳定中间体（如芳炔、环炔等）的组合，其将被并行产生，将被研究以提供一种容易获得高度官能化的杂环。除了已知的好处，如改善辐射和加速反应以及更好地混合反应物，我们希望建立在芯片实验室技术的内在分析优势，将其应用于双重和协同催化剂的挑战性优化。

The proposed project is focussed on photochemical and/or photocatalytical flow-based syntheses in classical flow or microchip reaction systems. In this context, the combination of photoredox catalytic reactions with instable intermediates (such as arynes, cyclic alkynes etc.), which will be generated in parallel, will be investigated to provide a facile access to highly functionalized heterocycles. In addition to the known benefits like improved irradiation and acceleration of the reaction as well as better mixing of the reactants, we want to build on the intrinsic analytical advantages of lab-on-a-chip technology to apply these in challenging optimizations of dual and synergistic catalyses.