Application of novel exact combinatorial optimisation techniques and metaheuristic methods for problems in cancer research

新的生物技术为了解癌症发生和发展的遗传基础提供了一个前所未有的机会。然而，它们给我们带来了挑战；需要引入新的计算方法和改进的数学模型和算法来补充这些技术，以确定我们个人基因构成的功能，特别是与疾病状态有关的功能。该项目将处理与澳大利亚一些发病率最高的癌症相关的研究问题和数据集。该项目将有助于开发新的功能强大的模式识别算法，用于未来的“个性化”分子诊断方法。

Novel biotechnologies are offering an unprecedented opportunity to understand the genetic basis of cancer development and progression. However, they present us with a challenge; new computational methods and improved mathematical models and algorithms need to be introduced to complement these technologies in the determination of the function of our individual genetic makeup, especially in connection with disease states. The project will deal with research questions and datasets related to some of the highest incidence cancers in Australia. This project will contribute towards the development of new powerful algorithms for pattern recognition for future "personalized" molecular diagnostics methods.