Goal pursuit despite emotional distraction: Neural-network mechanisms of emotional interference inhibition and their role for resilience (C04)

情绪干扰抑制（EII），即，抑制显著的情绪刺激以追求目标导向的行为，尽管情绪分散，被认为是一般的弹性机制。在第一个资助期内，我们已经确定了一个大脑网络，该网络具有各种类型EII共同的特定光谱特征，并与弹性的代理指标相关。使用信息理论，药理学和神经调节的方法，我们现在的目标是获得机械和因果关系的理解，这个网络的功能及其作为一个弹性机制的作用。

Emotional interference inhibition (EII), i.e., inhibition of salient emotional stimuli to pursue goal-directed behavior despite emotional distraction, is considered a general resilience mechanism. In the first funding period, we have identified a brain network with specific spectral signatures common to various types of EII and correlating with proxy measures of resilience. Using information theoretic, pharmacological and neuromodulatory approaches, we now aim to gain mechanistic and causal understanding of the function of this network and its role as a resilience mechanism.