High-Pressure Liquid Chromatography Triple Quadrupole Mass Spectrometer with highest sensitivity (HPLC-MS/MS)

HPLC-MS/MS系统扩展了可以检测到的微量化合物的光谱，补充了土壤科学与土壤保持研究所建立的提取方法（加压液体提取，超声波提取，微波辅助提取）。在这种情况下，质谱/质谱检测对于确保在复杂基质中进行可靠的定量，以及对代谢物和“新出现的污染物”进行有针对性的筛选至关重要。三重四元质谱技术的这种优势在化学食品分析领域也很重要，例如用于残留物浓度的定量，以及在昆虫生物技术领域研究天然化合物的生产和应用。随着Jan Siemens教授被任命为土壤资源教授，土壤科学与土壤保持研究所加强了对土壤中污染物（特别是药物）命运的研究重点。因此，土壤和相关环境区室中极性污染物的痕量分析目前得到了扩展。由于iFZ和邻近研究所的HPLC-MS/MS仪器的大量容量利用率，这种结合MS/MS接口和光电二极管阵列检测器的多功能设备的应用，对极性有机化合物的痕量浓度进行敏感定量，也得到了其他工作组的坚持支持。

The HPLC-MS/MS system extends the spectrum of trace compounds that can be detected complementary to the extraction methods established at the Institute of Soil Science and Soil Conservation (Pressurized liquid extraction, ultrasonic extraction, microwave-assisted extraction). In this context the MS/MS detection is essential for ensuring reliable quantification in complex matrices, as well as for targeted screenings for metabolites and “emerging pollutants”. This strength of the triple-quad MS technique is also important in the fields of chemical food analysis, e.g. for the quantification of residue concentrations, and of interest in the field of insect biotechnology for research addressing the production and application of natural chemical compounds.With the appointment of Prof. Jan Siemens as Professor of Soil Resources the Institute of Soil Science and Soil Conservation strengthens it research focus regarding the fate of pollutants (esp. pharmaceuticals) in soils. Therefore, the trace analysis of polar pollutants in soils and related environmental compartments is currently extended. Due to the large degree of capacity utilization of HPLC-MS/MS instruments at the iFZ and neighboring institutes, this application for a versatile device with a combination of MS/MS interface and photodiode array detector for the sensitive quantification of trace concentrations of polar organic compounds is supported insistently also by other working groups.