Cellular uptake of glutathione transferases and their development as cell transfection agents

所有细胞的功能和生存需要大量的生化试剂的输入。 为了实现这一点，这些试剂必须穿过细胞膜壁运输。 我们正在研究一种新的传递系统，涉及酶谷胱甘肽转移酶（GST）。 通过研究GST如何穿过细胞膜，我们将能够开发一种将生物活性分子递送到细胞中的新技术。这项令人兴奋的新技术将应用于研究和治疗药物的输送，以治疗一系列疾病。

The function and survival of all cells requires the importation of a vast array of biochemical agents. In order for this to occur, these agents must be transported across the cell membrane wall. We are investigating a novel delivery system involving the enzyme glutathione transferase (GST). By investigating how GSTs cross membranes, we will be able to develop a new technology for the delivery of biologically active molecules into cells. This exciting new technique will have applications in research and in the delivery of therapeutic drugs for the treatment of a range of diseases.