Glutathione transferase Zeta: A novel regulator of glucose and lipid metabolism

谷胱甘肽转移酶 Zeta：糖脂代谢的新型调节剂

• 批准号: nhmrc : 1052556
• 负责人: Prof Philip Board
• 金额: $ 40.28万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/glutathione-transferase-zeta-lipid-metabolism/112284
• 关键词: Glutathione; transferase; Zeta; novel; regulator

Obesity is a problem of global significance as a cause of preventable illness and death. The many consequences of obesity including cardiovascular disease, type 2 diabetes, cancer and osteoarthritis are an increasing burden on affected subjects and on the health care system. Our recent studies have revealed a novel pathway for the regulation of obesity. This discovery has provided a new target for the development of drugs for obesity and related disorders.

肥胖是一个全球性的问题，是可预防的疾病和死亡的原因。肥胖症的许多后果，包括心血管疾病、2型糖尿病、癌症和骨关节炎，对受影响的受试者和医疗保健系统造成越来越大的负担。我们最近的研究揭示了一种调节肥胖的新途径。这一发现为肥胖及相关疾病药物的开发提供了新的靶点。