GENOMIC/PHENOMIC IDENTIFICATION AND CHARACTERISATION OF NOVEL HEMATOPOIETIC REGULATORS
GENOMIC/PHENOMIC IDENTIFICATION AND CHARACTERISATION OF NOVEL HEMATOPOIETIC REGULATORS
批准号:
DP0556154
负责人:
Prof Benjamin Kile
金额:
$29.45万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2005
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2005-01-01 至 2008-12-31
中文摘要
血细胞是健康的基础。它们在维持组织和器官的状态,对抗感染方面发挥着至关重要的作用,并且是身体对损伤反应的重要参与者。了解血细胞是如何产生的以及它们是如何发挥作用的,对于改善疾病的治疗至关重要。随着基因组的测序,我们现在有了找到控制这些过程的基因所需的工具。该项目将利用现代遗传技术的力量来剖析参与血细胞形成和功能的新基因的作用,并将为治疗与这一重要细胞系统失调相关的许多疾病开辟新的治疗机会。
英文摘要
Blood cells are fundamental to health. They play a vital role in maintaining the condition of tissues and organs, fight infections and are essential players in the body's response to injury. Understanding how blood cells are produced and how they function is critical to improving the treatment of disease. With the sequencing of the genome, we now have the tools we need to find the genes controlling these processes. This project will harness the power of modern genetic technologies to dissect the role of novel genes involved in blood cell formation and function, and will open up new therapeutic opportunities for treating the many diseases associated with dysregulation of this important cell system.
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会议论文
Elucidating the mechanisms of mitochondrial DNA escape
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批准号:DP200103637
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项目类别:Discovery Projects
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资助金额:$37.21万
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财政年份:2020
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负责人:Prof Benjamin Kile
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依托单位:
The role of apoptotic caspases in regulating type I interferon production
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批准号:nhmrc : 1077750
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项目类别:Project Grants
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资助金额:$52.79万
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财政年份:2015
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负责人:Prof Benjamin Kile
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依托单位:
The role of apoptotic caspases in regulating type I interferon production
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批准号:nhmrc : GNT1077750
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项目类别:Project Grants
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资助金额:$76.15万
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财政年份:2015
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负责人:Prof Benjamin Kile
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依托单位:
Understanding the genetics of blood cells and blood cell disorders
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批准号:nhmrc : GNT1063008
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项目类别:Research Fellowships
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资助金额:$72.76万
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财政年份:2014
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负责人:Prof Benjamin Kile
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依托单位:
The role of oncogenes, cell death machinery and novel players in the regulation of hematopoietic stem cells, leukemogenesis and hematological disorders
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批准号:nhmrc : 1063008
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项目类别:Research Fellowships
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资助金额:$50.9万
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财政年份:2014
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负责人:Prof Benjamin Kile
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依托单位:
Uncoupled Research Fellowship
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批准号:nhmrc : 575506
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项目类别:NHMRC Research Fellowships
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资助金额:$2.27万
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财政年份:2009
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负责人:Prof Benjamin Kile
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依托单位:
Role of the Ets family transcription factor Erg in stem cell function and hematopoiesis
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批准号:nhmrc : 516726
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项目类别:NHMRC Project Grants
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资助金额:$27.59万
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财政年份:2008
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负责人:Prof Benjamin Kile
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依托单位:
The genetic control of platelet production and function
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批准号:nhmrc : 461247
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项目类别:NHMRC Project Grants
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资助金额:$37.27万
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财政年份:2007
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负责人:Prof Benjamin Kile
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依托单位:
A phenomic and genomic approach to identifying pharmaceutical targets for the amelioration of hematopoietic deficit
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批准号:nhmrc : 305541
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项目类别:Early Career Fellowships
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资助金额:$5.8万
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财政年份:2004
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负责人:Prof Benjamin Kile
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依托单位:
海外基金