Development of functional nano-particles using biomineralization process in magnetic bacteria

我们开发了一种利用趋磁细菌的磁铁矿生物矿化蛋白合成功能纳米颗粒的方法。纳米颗粒的形状、大小和磁性能是由负责磁铁矿晶体形成的蛋白质调控的。利用Bar结构域蛋白控制纳米晶体合成的空间，利用铁转运蛋白建立脂质体的顺序晶体形成过程。本研究制备的纳米粒子将作为纳米材料应用于生物技术和磁记录等领域。

We developed a method for synthesis of functional nano-particles using proteins involved in magnetite biomineralization of magnetotactic bacteria. Shape, size and magnetic property of nano-particles were regulated by using proteins responsible for magnetite crystal formation. Bar domain protein was used to control space for nano-crystal synthesis, and iron transporter protein was used for establishment of sequential crystal formation process in liposomes. The nano-particles developed in this study will be used as nano-materials in the fields of biotechnology and magnetic recordings.