Multistimuli sensing with memory and feedback function using photoswitchable proteins and coordination chemistry (B04)

我们将开发水凝胶中多刺激响应性交联物的分子工具箱，它可以感知和整合不同刺激作为输入(不同颜色的可见光、氧化还原、pH和金属离子)，并按照化学编码逻辑对它们做出反应。我们将探索这种水凝胶如何对先前的输入产生记忆，并使用内在产生的信号来产生反馈。对多种刺激作出反应的不同分子构件的整合及其相互作用将为水凝胶中分子水平的信息处理提供基础。

We will develop a molecular toolbox of multistimuli responsive crosslinks in hydrogels that can sense and integrate different stimuli as inputs (different colours of visible light, redox, pH and metal ions) and respond to them following a chemically coded logic. We will explore how such hydrogels can develop memory for previous inputs and use intrinsically generated signals to generate feedback. The integration of different molecular building blocks that react to multiple stimuli and their interplay will provide the basis of molecular level information processing within hydrogels.