Availability of magnesium
Availability of magnesium
批准号:
14370128
负责人:
CHIBA Momoko
金额:
$7.81万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2002
资助国家:
日本
项目状态:
已结题
起止时间:
2002 至 2003
中文摘要
镁(Mg)是一种众所周知的元素,也是人体和动物的必需元素之一。在营养领域,镁对人类具有可接受的剂量,2000年膳食镁参考摄入量设定为300 mg/天,上限为700 mg/天,尽管数值根据性别和年龄略有变化。迄今为止,还没有关于镁过量或缺乏引起的人体毒性的报道。根据我们以前的研究结果,我们集中在镁对生殖功能和存活率的影响。缺镁组在正常饲料组(含镁494.4mg/kg)基础上加喂低镁饲料(含镁42.4mg/kg)。向两个独立的公司A和B订购镁缺乏饮食。缺镁饲料组与对照组的成活率有显著差异。这一事实可能是由共存的矿物含量解释。至于性激素的影响,它也可以被认为是饮食的成分:即男性血液中的睾酮浓度下降后,镁缺乏后,虽然女性的雌激素没有变化。饮食准备不同的公司也影响到结果的激素的影响。在研究矿物时,必须考虑矿物之间的相互作用。
英文摘要
Magnesium (Mg) is one of universally well-known elements, and one of the essential elements in human and animals. In the nutrition fields Mg has a recommendable dose for human beings, and in 2000 the dose of dietary reference intake of Mg was set at 300 mg/day, and upper limit at 700 mg/day, although the values were slightly shifted depending upon the sex and ages. It has not reported human toxicity due to over dosage or deficient illness of magnesium up to now. Based upon the results of our previous study we have focused on the effects of magnesium on reproductive function and the survival rates. Mice of Mg-deficient group were given low Mg diet (Mg content 42.4mg/kg) in addition to the normal diet group (Mg content 494.4mg/kg). Mg deficient diets were ordered to two independent companies, A and B). After giving Mg deficient diets survival rates were much different from 2 diet groups. This fact might be explained by the coexisting mineral contents. As to the effects of sex hormones, it could be also considered as the ingredients of diets : namely testosterone concentration in blood in males decreased after Mg deficiency although that of estrogen in females showed no change. Diets prepared different companies also influenced to the results of hormonal effects. When we investigate minerals, it should be important to be taken account to the interaction of minerals.
期刊论文(2)
专著(0)
科研奖励(0)
会议论文
Inflammatory response and cathepsins in silica-exposed Hermansky-Pudlak syndrome model pale ear mice
DOI:
10.1111/j.1440-1827.2004.01626.x
发表时间:
2004-05-01
期刊:
PATHOLOGY INTERNATIONAL
影响因子:
2.2
作者:
[Yoshioka, Y, Kumasaka, T, Fukuchi, Y]
通讯作者:
Fukuchi, Y
Health Effects of Rare Earth Elements
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批准号:23590753
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.33万
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财政年份:2011
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负责人:CHIBA Momoko
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依托单位:
アラル海の縮小に伴う附近住民の健康被害調査-ウラニウムを中心に-
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批准号:16256003
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$15.97万
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财政年份:2004
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负责人:CHIBA Momoko
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依托单位:
Mechanism of metabolism and function of rubidium in body
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批准号:12470088
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$2.37万
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财政年份:2000
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负责人:CHIBA Momoko
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依托单位:
Health problem due to magnesium and/or potassium deficiency-Experimental study using stable isotope-
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批准号:09470104
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.87万
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财政年份:1997
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负责人:CHIBA Momoko
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依托单位:
Effects of thallium on biological bodies
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批准号:04670315
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1992
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负责人:CHIBA Momoko
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依托单位:
MECHANISMS OF INTERACTION OF TIN AND OTHER ELEMENTS IN MICE AND IDENTIFICATION OF TIN-BINDING PROTEIN IN ORGANS
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批准号:63570242
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.22万
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财政年份:1988
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负责人:CHIBA Momoko
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依托单位:
海外基金