"Man-Earth System : A scientific approach to realize human society in harmony with the Earth"-Transgenerational Effects of Man-made Environmental Toxic Agents Contaminating the Earth-

为了研究污染地球的人造有毒物质的跨代影响，我们的研究重点如下：a)暴露于人造有毒物质（如二恶英和草甘膦）的小鼠、大鼠和鱼类的后代会出现形态和功能异常。b)邻苯二甲酸盐破坏红细胞，然后通过缺氧杀死精子。c)克隆了重复序列探针Pc-3，用于检测辐射暴露小鼠后代的异常多态性。d)切尔诺贝利灾难后放射性核素的生态和遗传研究：在蘑菇、浆果等中观察到放射性核素的高生物浓度。除野生动物和实验动物（如青蛙、果蝇）外，还在人类中检测到遗传效应。

We focus the followings to examine the transgenerational effects of man-made toxic agents contaminating our planet :a) Morphological and functional abnormalities were induced in the offspring of mice, rats, and fish exposed to man-made toxic agents such as dioxin and glyphosate.b) Phthalate gives damage to erythrocytes, and then kills sperm by anoxia. Dioxin may injure the seminal vesicle preceeding the damage to germ cells.c) Repetitive sequence probe Pc-3 was cloned to detect anomalous polymorphism in the offspring of mice exposed to radiation.d) Ecological and genetic studies of radionuclides after Chernobyl catastrophe : Strong biological concentration of radionuclides was observed in mushroom, berries, etc. Genetic effects were detected in human in addition to wild and experimental animals (e.g., frog, Drosophila).