A five-year longitudinal study on the change of and the determinant of bone mass gain at lumbar spine and hip during adolescence : the prevention of fracture on adolescence and osteoporosis from adolescence

在京都3所初中的412名一年级学生中，我们通过DXA测量了腰椎（L2-L4）和全髋关节的HMD、身高、体重和基线握力。通过每隔一年进行的调查，对这一队列进行了为期4年的随访。我们在346名初中三年级学生（127名男生和219名女生，随访率=84.0%）和205名高中二年级学生（79名男生和126名女生，随访率除了那些不能通过转学继续学习的学生=55.5%）中检查了相同的变量。我们的研究得出了五个结果：1.从初中一年级到高中二年级，男女学生的腰椎和全髋骨密度均明显增加，并且在年级和地点的骨密度变化率上存在性别差异。由于BMD从基线到初中三年级的变化率^<#1>比从初中三年级开始的变化率^<#2>增加更大，因此， ...更多信息 从小学到高中二年级，初中阶段是骨量增加的重要时期。2.年龄越大，男性和女性的脊柱和髋部骨密度越高。3.男性和女性脊柱和髋部骨密度均随体重增加而增加。体重管理对骨量的获得很重要。4.初中或高中时期运动生活方式较积极的男女生，其脊柱和髋部的骨密度较高。初中和高中阶段的体育活动是青春期前后男女儿童腰椎和全髋骨发育的重要决定因素。5.初中和高中阶段充足的钙摄入量被认为对骨密度的获得有积极的影响，尽管骨密度与钙摄入量之间没有显著的关系。1)腰椎：男孩=10.4%/年，女孩=6.0%/年;全髋关节：男孩=8.6%/年，女孩=5.3%/年#2）腰椎：男孩=6.1%/年，女孩=2.8%/年;全髋关节：男孩=3.5%/年，女孩=2.0%/年减

For 412 first-grade students at 3 junior high schools in Kyoto, we measured HMD by DXA at the lumbar spine (L2-L4) and total hip, height, weight, and grip strength at baseline. This cohort was followed for 4 years through surveys conducted every other year. We examined the same variables in 346 third-grade junior high school students (127 boys and 219 girls, follow-up rate=84.0%) and 205 second-grade high school students (79 boys and 126 girls, follow-up rate excepting those who cannot pursue by transfer=55.5%). Our research produced five results.1.There was a significant increase in BMD at the lumbar spine and total hip from the first year of junior high school to the second year of high school in both genders, and the gender differences in the rate of change in BMD for both grade levels and sites were observed. Since the rates of change^<#1> in BMD from the baseline to the third-grade in junior high schools have a larger increase than those^<#2> from the third-grade in junior high sc … More hools to the second-grade in high schools, the junior high school period is very important for bone mass gain.2.The more mature subjects had a higher BMD at spine and hip in both sexes. However, an inverse relationship was observed between the maturation stage and the annual change rates in BMD.3.BMD at the spine and hip increased with weight in both sexes. Weight management is important for the acquisition of bone mass.4.The boys and girls with more active sporting lifestyles in junior high or high school showed greater BMD at spine and hip. Sporting activity at junior high school age and high school age was the important determinant of bone development at the lumbar spine and total hip in peripubertal boys and girls.5.Sufficient calcium intake for the junior high school and high school period was considered to influence the acquisition of bone density positively, although there was no significant relationship between BMD and calcium intake.#1)lumbar spine : boys=10.4%/yr, girls=6.0%/yr ; total hip : boys=8.6%/yr, girls=5.3%/yr#2)lumbar spine : boys=6.1%/yr, girls=2.8%/yr ; total hip : boys=3.5%/yr, girls=2.0%/yr Less