Drug particle characterisation

了解药物颗粒的特性是开发新型靶向给药鼻腔喷雾器的关键问题之一。利用最新的实验和数值技术，对喷雾器中药物形成和鼻腔内颗粒沉积进行了全面的研究。将开发一种计算机辅助设计技术来优化给药系统。这项新技术在开发先进/创新的药物给药系统和评估通过鼻子引入的药物的潜在生物效应方面具有巨大的治疗和经济效益。

The understanding of drug particle characterizations is one of the key issues in the development of novel nasal sprayers for targeted drug delivery. A comprehensive study is proposed for characterising drug formation in sprayers and particle deposition in nasal cavity using the latest experimental and numerical techniques. A computer-aided design technology will be developed to optimise drug delivery systems. The new technology has great potentials leading to therapeutic and economic benefits in developing advanced/innovative drug delivery systems and in evaluating the potential biological effects by the drugs to be introduced through the nose.