CONNECTION SELECTIVITY IN CEREBRAL CIRCUITRY

阐明新皮层组织的原则是理解大脑皮层功能的关键。我们定量鉴定了兴奋性锥体细胞和GABA能非锥体细胞亚型。我们发现，神经元亚型表现出选择性连接，GABA能细胞在局部和整体节律放电。因此，在新皮层的局部突触组织和放电活动指定根据全球区域间的电路和它们的振荡相互作用。

Elucidation of neocortical organization principles is crucial for understanding the function of the cerebral cortex. We quantitatively identified excitatory pyramidal and GABAergic nonpyramidal cell subtypes. We found that the neuron subtypes exhibited selective connectivity and that GABAergic cells discharged during the local and global rhythms. Thus, the local synaptic organization and firing activity in the neocortex are specified according to global inter-regional circuits and their oscillatory interaction.