Small Molecule NMR Facility for Accelerated Drug Discovery

该项目将通过建立世界级的小分子核磁共振（NMR）设备来加速药物发现过程。所要求的仪器将实现合成先导化合物的高通量结构分析，加快天然产物的分离和鉴定，并增强基于核磁共振的药物筛选。该设施将支持维多利亚州大学的现有和新项目，特别是药物和生物化学，并实现具有国际竞争力的研究能力。成果将包括开发新药，增加本地和国际合作，培训新科学家使用最先进的光谱技术来鉴定天然产物和具有药理重要性的合成分子。

This project will accelerate the drug discovery process by establishing a world-class small-molecule Nuclear Magnetic Resonance (NMR) facility. The requested instrumentation will enable high throughput structural analysis of synthetic lead compounds, expedite natural product isolation and identification and enhance NMR-based drug screening. This facility will support both existing and new programs in Victorian universities, particularly Medicinal and Biological Chemistry, and achieve internationally competitive research capabilities. Outcomes will include the development of new pharmaceuticals, increased local and international collaboration and the training of new scientists in state-of-the-art spectroscopic techniques for identification of natural products and synthetic molecules of pharmacological importance.