The heterogeneity of various Porphyromonas gingivalis strains to adherence and invasive.
The heterogeneity of various Porphyromonas gingivalis strains to adherence and invasive.
批准号:
02670816
负责人:
NAITO Yuko
金额:
$1.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for General Scientific Research (C)
财政年份:
1990
资助国家:
日本
项目状态:
已结题
起止时间:
1990 至 1991
中文摘要
牙龈卟啉单胞菌与成人牙周炎有关。这种生物已经被证明附着在胶原蛋白上,胶原蛋白是牙龈组织的主要成分。此外,我们发现不同牙龈假单胞菌对胶原包被透明质酸的附着存在明显的异质性。无毒菌株粘附于口腔组织的程度高于毒力菌株粘附于龈沟的程度。我们还澄清了牙龈卟啉菌对十六烷的吸附与它们附着在羟基磷灰石表面形成的拼贴物上的数量之间的总体相关性。我们的研究证明了菌株疏水性的差异可能是由于不同的菌毛能够附着在胶原包被的透明质酸上。另一方面,囊泡具有粘附性,无论毒性如何,囊泡都粘附在膜或胶原包被的羟基磷灰石上。
英文摘要
Porphyromonas gingivalis has been associated with adult periodontitis in human. The organism has been shown to attach to collagen which is major component gingival tissue. Moreover, we found that there were clear heterogeneity among P. gingivalis strains in their attachment to collagen coated HA. Avirulence strains adherent to oral tissue much than virulence strains in gigival sulcus. We have also clarified that an overall corelation was noted between the adsorption of strains P. gingivalis to hexadecane and their numbers which attached to collage formed on hydroxyapatite surfaces. Our study has proved the evidence that the difference in hydrophobic properties of strains may be due to difference of fimbriae which has appeared to be capable of attachment to collagen coated HA. On the other hand, vesicles have the adhesion which were adherent to pellicle or collagen coated hydropxyapatite regardless of virulence.
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Y.Naito,K.Okuda,I.Takazoe: "Comparatiwe hydrophobicity of various Porphyroーmonas gingivalis strains and their adherence to collagen substrate"
Y.Naito、K.Okuda、I.Takazoe:“不同牙龈卟啉单胞菌菌株的疏水性比较及其对胶原基质的粘附”
DOI:
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作者:
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通讯作者:
Y. Naito: Analysis of adherence mechanizum of periodontal bacteria. Shikwa gakuhou, 92 (1992)
Y. Naito:牙周细菌粘附机制的分析。
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通讯作者:
内藤 祐子: "歯周病原菌の付着機序についての解析" 歯科学報. 92. (1992)
内藤裕子:“牙周病原菌的粘附机制分析”牙科杂志92。(1992)
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通讯作者:
K. Ishihara, Y. Naito, et al: "A sensitive enzymatic method (SK-013) for detection and quantification of specific periodontopathogens" J Periodont Res. 26. (1992)
K. Ishihara、Y. Naito 等人:“用于检测和定量特定牙周病原体的灵敏酶法 (SK-013)”J periodont Res。
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作者:
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通讯作者:
Y.Naito,et al.: "Attachment of Porphyromonas gingivalis fimbriae and vesicle to collagenous substrata." J.Dent.Res.70. 316 (1991)
Y.Naito 等人:“牙龈卟啉单胞菌菌毛和囊泡附着在胶原基质上。”
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共 14 条
Elucidation of regulatory mechanism of B cell activation by the change in sialic acid species
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A STUDY ON RELATIONSHIP BETWEEN STOMATOGNATHIC SYSTEM AND SPORTS PERFORMANCE
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ISOLATION AND SOME PROPERTIES OF ADHERENT MATERIALS OF PORPHYROMONAS GINGIVALIS
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财政年份:1993
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Attachment and invasion of periodontopathic bacteria tosubgingival site
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财政年份:1988
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A basic study on the development of diagnostic and treatment for periodontal diseases using monoclonal antibodies against human periodonopathic bacteria.
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依托单位:
海外基金