Assessment of Vital Age in Japanese Adult Men and its Validity.

我们最近开发了一个有用的方程，用于估计日本男性的生命年龄（VA）或所谓的生物年龄，该方程包括10个预测因子，这些预测因子基于不仅在休息状态下而且在运动期间测量的各种生理因素的评估。然而，一般来说，在特定群体中开发的任何方程都具有群体特异性的缺点。群体特异性可能是由于自变量的多重共线性，当将方程应用于具有不同自变量多元结构的组时，这会导致误差。最初的分析提供了方程有效性的证据，但最有力的证据是通过交叉验证研究获得的。本研究的目的是确定VA作为身体健康和/或老化状态的敏感指标的交叉效度，从横截面和纵向的观点。对数据的分析表明，实际年龄（CA：56.6（）SY. ±。()7.9 VA（56.10 ± 0.05）SY. ()9.9 42例正常人VA为65.1 ± 0.05岁，男性冠心病患者（n=22）的CA（10.9岁; 48.7-86.2岁）明显低于其CA（56.4 ± 0.5岁）。()8.9年龄; 41-70岁）。VA和CA之间的相关性在明显健康的男性中为r=0.76，在CHD患者中为r=0.62。我们重申，VA可以是身体健康和/或衰老状态的有效指标。

We have recently developed a useful equation for estimating vital age (VA) or the so-called biological age of Japanese men, which consists of 10 predictors based on the assessment of various physiological factors measured not only during a state of rest but also during exercise. In general, however, any equations developed in a certain population have the disadvantage of population-specificity. The population-specificity may be due to the multicollinearity of the independent variables, which causes errors when the equations are applied to groups with different multivariate structures of the independent variables. The original analysis provides evidence of an equation's validity , but the strongest evidence is obtained with cross-validation research. The purpose of this study was to determine the cross-validity of VA as a sensitive index of physical health and/or aging status from both the cross-sectional and longitudinal standpoints. Analyzes of the data indicated that there was no significant difference between chronological age (CA : 56.6(〕SY.+-.〔)7.9 yr) and VA (56.1(〕SY.+-.〔)9.9 yr) in the normal men (n=42), while the mean VA (65.1(〕SY.+-.〔)10.9 yr ; 48.7-86.2 yr) of male patients with coronary heart disease (n=22) was significantly lower than their CA (56.4(〕SY.+-.〔)8.9 yr ; 41-70 yr). Correlations between VA's and CA's were r=0.76 in apparently healthy men and preintervention r=0.62 in CHD patients. We reiterate that VA could be a valid index of physical health and/or aging status.