Dissecting the Brain Circuitry Shaping Fear Regulation Across Development

青春期是一个重要的时期，人们学会管理与压力相关的情绪，如恐惧。该项目旨在了解大脑前额叶皮层的成熟变化如何阻碍青少年学习减少对威胁的反应。它的目标是通过剖析青春期前、青春期和成年期形成学习、记忆和情绪调节的大脑回路来实现这一目标。该项目希望产生新的知识，解释为什么大脑的发育变化对于成熟的学习和记忆形式是必要的。该项目的预期结果包括对发育中的大脑有更丰富的了解，这将最终为改善青少年情绪调节的方法提供信息。

Adolescence is an important time when individuals learn to manage stress-related emotions like fear. This project aims to understand how maturational changes in the prefrontal cortex of the brain hinder adolescents when learning to reduce reactivity to threats. It aims to do so by dissecting the brain circuitry shaping learning, memory, and emotional regulation across pre-adolescence, adolescence, and adulthood. The project expects to generate new knowledge about why developmental changes in the brain are necessary for mature forms of learning and memory. The expected outcomes of this project include a significantly richer knowledge of the developing brain, which will ultimately inform approaches for improving emotion regulation in youth.