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Dietary therapy of diabetes mellitus with tartary buckwheat

Dietary therapy of diabetes mellitus with tartary buckwheat
苦荞治疗糖尿病的食疗
批准号:
10680164
负责人:
SHIZUKA Fujiko
金额:
$1.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
1998
资助国家:
日本
项目状态:
已结题
起止时间:
1998 至 1999

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中文摘要
翻译
在鞑靼袋热的应用中,含有大量的鲁丁,在Otsuka Long-Evans Tokushima Fatty (OLETF)大鼠中评估了糖尿病阳性疗法,一种非胰岛素相关糖尿病阳性阳性(NIDDM)模型。在实验1中,糖尿病动物被赋予了实验性饮食,含有20%的焦油泡沫,用8周的时间来评估饮食治疗的影响。控制饮食含有普通的起泡剂或不含有补充剂的起泡剂。No effective observation of tartary buckwheat as compared with common buckwheat was obtained in the results of oral glucose Tolerance test and blood hemoglobin AイイD21cイエD2%。在实验2中,糖尿病症状体的发展中的Buckwheat的预防效果在年轻(6周老) OLETF大鼠中被评估。他们已经在28周的时间里喂养了实验性饮食。在中国,一种商业上可用的基于糖尿病患者的基于烟草袋热的混合配方已被用于添加到烟草和普通烟草热。混合物是什么 ... More 它由54%的焦油泡沫、24%的南瓜、16%的黑大豆和6%的中国口香糖组成。口服葡萄糖耐受性测试每4周进行一次测试。等离子体胰岛素,血球蛋白A,D21 c,D2和urinary albumin excretion were measured periodically。从患有高胰岛素的血液葡萄糖的异常概况中,NIDDM的一次估计在这个模型中大约20周旧。Daibetic Profile进一步开发与年龄。关于动物饲养的鞑靼箱热饮食的一半数字,如良好地控制饮食,如没有包含箱热,减少身体重量到疾病的严重程度,与高胰岛素、高血红蛋白A-D21 c-D2 %和增加的原始专辑异常相结合。老鼠喂养的饮食与普通的buckwheat和tartary buckwheat基于混合物,如何,没有显示这样的严重症状可以通过实验期。结果演示表明,buckwheat是有益的应用于NIDM的饮食治疗,当大剂量的rutin可能不会被推荐用于治疗。Less(低)
英文摘要
Application of tartary buckwheat, which contains high amount of rutin, for dietary therapy of diabetes mellitus was evaluated in the Otsuka Long-Evans Tokushima Fatty (OLETF) rats, a model of non insulin dependent diabetes mellitus (NIDDM). In experiment 1, diabetic animals were given experimental diet containing 20% tartary buckwheat flour for 8 weeks to evaluate the effect of dietary treatment. Control diets contained common buckwheat with or without supplemented rutin. No effective observation of tartary buckwheat as compared with common buckwheat was obtained in the results of oral glucose tolerance test and blood hemoglobin AィイD21cィエD2%. In experiment 2, preventive effect of buckwheat on the development of diabetic symptoms was evaluated in young (6-week-old) OLETF rats. They were fed experimental diets for 28 weeks. Commercially available tartary buckwheat-based mixture formulated for diabetic patients in China was used in addition to tartary and common buckwheats. The mixture wa … More s composed of 54% tartary buckwheat, 24% pumpkin, 16% black soybean and 6% chinese yam. Oral glucose tolerance test was performed every four weeks. Plasma insulin, hemoglobin AィイD21cィエD2 and urinary albumin excretion were measured periodically. From the abnormal profile of blood glucose with hyperinsulinemia, the onset of NIDDM was estimated around 20-week-old of this model. The daibetic profile further developed with age. About half numbers of the animals fed tartary buckwheat diet, as well as control diet which did not contain buckwheat, decreased body weight owing to the seriousness of the disease, accompanied with disappearance of hyperinsulinemia, higher hemoglobin AィイD21cィエD2% and increased urinary albumin excretion. Rats fed diets with common buckwheat and tartary buckwheat-based mixture, however, did not show such serious symptoms throughout the experimental period. The result demonstrates that buckwheat is beneficially applied for diet therapy of NIDDM, whereas large dose of rutin might not be recommended for the therapy. Less
期刊论文(7)
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会议论文
志塚ふじ子: "ソバ粉摂取によるOLETEラットの糖尿病症状の進展抑制"OLETFラット研究会記録集. 最終巻. 92-95 (1999)
Fujiko Shizuka:“通过摄入荞麦粉抑制 OLETE 大鼠糖尿病症状的进展”OLETF 大鼠研究组记录 92-95 (1999)。
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志塚ふじ子: "OLETFラットの病態に対するダッタンソバの効果" OLETFラット研究会記録集. 第4巻. 63-66 (1998)
Fujiko Shizuka:“Dattan Soba 对 OLETF 大鼠病理状况的影响”OLETF 大鼠研究组记录,第 4 卷,63-66 (1998)。
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Fujiko SHIZUKA: "Buckwheat prevented the development of diabetic symptoms in OLETF rats"J. OLETF rat Res.. 5. 92-95 (1999)
Fujiko SHIZUKA:“荞麦可以预防 OLETF 大鼠糖尿病症状的发展”J.
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志塚ふじ子: "OLETFラットの病態に対するダッタンソバの効果"OLETFラット研究会記録集. 第4巻. 63-66 (1998)
Fujiko Shizuka:“Dattan Soba 对 OLETF 大鼠病理状况的影响”OLETF 大鼠研究组记录,第 4 卷,63-66 (1998)。
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