课题基金 / 基金详情

Analysis of anticarcinogenesis on apple pectin-mechanisum of inhibitory on free radical and DNA damage

Analysis of anticarcinogenesis on apple pectin-mechanisum of inhibitory on free radical and DNA damage
苹果果胶抗癌作用分析——抑制自由基和DNA损伤的机制
批准号:
12671148
负责人:
TAZAWA Kenji
金额:
$2.11万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2000
资助国家:
日本
项目状态:
已结题
起止时间:
2000 至 2002

项目摘要

项目成果

TAZAWA Kenji的其他基金

相似基金

相关文献

中文摘要
翻译
通过将苹果皮素衍生出的寡氯烷化合物从2000年4组平均聚合化程度来区分,对DNA测试中氧化物损伤预防的影响。它是明确的,因为自由基的清除是使用ESR在每个低分子区域中的一种很高的方法。这个低分子区域的苹果蛋白的商品化已经尝试过,D1和D2的含有22.5%的低分子寡链化合物已经开发出来。低分子低分子寡链化合物的高功能苹果被引入人类,并澄清了血液流动速度分解是如何改进的,使用MC-FAon清除活动用于ONOO^-,它证明POS-S组件是2.4 (标题),加热POS-S的POS-H是80.8,当它被测试使用DCDHF。低分子寡氯代化合物商业化的高功能苹果蛋白展示了26.6。ROO的清除活动是由DPPH测试的。低分子寡链化合物的高功能苹果提取物显示出2.04的价值,而它是最高的4.47,用于商业化低分子寡链化合物作为未来问题,它可能是低分子寡链化合物的高功能苹果提取物的完成,以防止DNA损伤。此外,这也是必要的,对人类8-OHdG产生率的抗氧化能力进行测试,并对预防生活方式的习惯做出了贡献,并通过商业化低分子高分子高分子低分子的高功能苹果片
英文摘要
By dividing the oligosaccharide of apple pectin derivation by mean degree of polymerization in 4 groups from 2000 ear, the effect for the prevention of the oxidative damage for DNA was examined. It was clarified that the scavenging for free radical was high method in each fractionation of the low-moleculer region using the ESR. The merchandizing of the apple pectin of this low-moleculer region was tried, and 22.5% inclusion low-moleculer oligosaccharide of D1 and D2 was developed. The high-functional apple pectin of low-moleculer oligosaccharide was taken to the human, and it was clarified that the blood flow velocity decreased how the hemodynamics is improved, using MC-FAOn scavenging activity for ONOO^-, it was proven that POS-S component was 2.4 (titer) and POS-H of heated POS-S was 80.8, when it was examined using DCDHF. High-functional apple pectin of low-moleculer oligosaccharide commercialized showed 26.6. The scavenging activity for ROO ・ was examined by DPPH. The high-functional apple pectin of low-moleculer oligosaccharide showed the value of 2.04, and it was the highest 4.47 on commercialized low-moleculer oligosaccharideAs future problem, it may be the completion of high-functional apple pectin of low-moleculer oligosaccharide to prevent a DNA damage. Also, it is necessary to examine the antioxydation power for 8-OHdG generation rate in the human and is regarded as contributing to the prevention of the lifestyle habit illness to people with many risk factors, by commercializing the high-functional apple pectin of low-moleculer oligosaccharide
期刊论文(31)
专著(0)
科研奖励(0)
会议论文
Tazawa K., Koike J., Namikawa H., Yatuzuka M et al.: "Characteristics on scavenging activity for free radic al in the Kampo medicine which suppresses hepatic met astasis"Kanpo-Medicine. 25. 15-19 (2001)
Tazawa K.、Koike J.、Namikawa H.、Yatuzuka M 等人:“抑制肝转移停滞的汉方药中自由基清除活性的特征”Kanpo-Medicine。
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
Tazawa K., Mizushima Y.: "Natural Apple Pectin-The mystery in the intestine by male and female"IRUKA BOOKS. 1-188 (2002)
田泽K.,水岛Y.:“天然苹果果胶-男性和女性肠道中的奥秘”IRUKA BOOKS。
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
田澤賢次: "汚れた腸をきれいにしてガンも活性酸素の害を防ぐアップルペクチンが豊富な焼きリンゴ"安心. 10. 40-42 (2003)
Kenji Tazawa:“富含苹果果胶的烤苹果,可以清洁肮脏的肠道,预防癌症和活性氧的危害” Anshin 10. 40-42 (2003)。
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
田澤賢次: "リンゴ繊維アップルペクチンが体重の増加を明らかに抑えることが判明"ゆほびか. 9. 66-67 (2001)
Kenji Tazawa:“苹果纤维苹果果胶明显抑制体重增加”Yuhobika。 9. 66-67 (2001)
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
共 31 条
    Inhibitory effects of apple pectin on experimental hepatic metastasis and portal free radical
    An analysis of inhibitory mechanism of colonic carcinoma and hepatic metastasis by apple pectin
    Analysis of the mechanism of colonic carcinoma transference depression by apple pectin.
    • 批准号:
      06671189
    • 项目类别:
      Grant-in-Aid for General Scientific Research (C)
    • 资助金额:
      $1.34万
    • 财政年份:
      1994
    • 负责人:
      TAZAWA Kenji
    • 依托单位:
    A Study of Super-selective Hyperthermia Using Dextran Magnetite Particles
    • 批准号:
      03454299
    • 项目类别:
      Grant-in-Aid for General Scientific Research (B)
    • 资助金额:
      $3.78万
    • 财政年份:
      1991
    • 负责人:
      TAZAWA Kenji
    • 依托单位:
    海外基金