Analysis of physiological functions of the fission yeast ammonium transporters

在微生物和植物中，氨是一种重要的氮源，用于氨基酸合成。微生物和植物都有吸收它的机制。本研究以裂变酵母菌为模型，研究了铵转运体的生理功能，它介导铵的跨膜转运。研究发现，铵转运体不仅在从环境中吸收铵的过程中起作用，而且在低铵诱导的酵母菌向丝状形态的分化和代谢产生的胞内铵的保留过程中起着重要作用。

In microorganisms and plants, ammonium is an important nitrogen source that is used for amino acid synthesis. Microorganisms and plants have mechanisms of its uptake. In this study, fission yeast was used as a model to elucidate physiological functions of ammonium transporter, which mediate transport of ammonium across the membrane. It has been found that ammonium transporter plays a role not only in uptake of ammonium from the environment but also in morphological differentiation from yeast to filamentous form induced by low ammonium and retention of intracellular ammonium produced from metabolism.