The role of circulating fibrocytes for cardiovascular remodeling

人外周血含有纤维细胞，可分化为其他间充质细胞，如肌成纤维细胞和脂肪细胞。在这项研究中，我们探讨了纤维细胞在心血管疾病中的作用。我们认为，在小鼠模型中，纤维细胞不是心血管疾病（如心肌梗塞、过度压力负荷和缺血性肢体疾病）的关键作用。

The human peripheral blood contains fibrocytes that can differentiate into other mesenchymal cells, such as myofibroblasts and adipocytes . In this study, we examined the role of fibrocytes in cardiovascular disease. We suggest that fibrocytes are not the critical role in cardiovascular disease such as infracted myocardium, over pressure load and ischemic limb disease in a mouse model.