Roles and possible treatment of lipoproteins in diabetic retinopathy

这项研究的目的是分析糖尿病视网膜病变的发生机制，并开发治疗这种疾病的新方法。糖尿病视网膜病变是糖尿病的主要并发症之一，可导致视网膜神经节细胞功能障碍。因此，对培养的视网膜神经节细胞进行损伤，分析神经元死亡的机制，并确定脂蛋白是否对神经元具有保护作用。本研究揭示了通过脂蛋白受体发挥神经保护作用的机制。

The aims of this study are to analyze mechanisms of development of diabetic retinopathy and to develop novel treatments for this disorder. Diabetic retinopathy is one of the major complications in diabetes and induces dysfunction of retinal ganglion cells (RGCs). Thus, RGCs in cultures were led injury, analyzed the mechanisms of neuronal death and determined whether lipoproteins protect neurons. This study showed the mechanism of neuroprotection via the receptor of lipoproteins.