Formation of sexually dimorphic neural circuitry and its function in the Drosophila chemosensory system

在黑腹果蝇中，在前腿踝部的味觉神经元中可以看到性别二态的投射模式。我们确定了每个味觉神经元的投射模式。结果表明，雄性神经元具有一些特定的刷毛，具有男性典型的投射。两种性别决定因素--无性和双性--调节着雄性特有的投射模式的形成。无性或双性功能丧失导致男性具有女性类型的投射模式。它们仍然表现出正常的求爱活动。

In Drosophila melanogaster, sexually dimorphic projection pattern is seen in the taste neurons on tarsus of the forelegs. We identified the projection pattern of each taste neuron. Results showed that the neurons with some specific bristles in males have male-typical projection. Two sex determination factors, Fruitless and Doublesex, regulate the formation of male-specific projection pattern. Loss of function of Fruitless or Doublesex caused males having female-type of the projection pattern. They showed the normal activity of courtship still.