Study on discharged antimicrobials into aquatic environment and presence of antimicrobial-resistant organisms

这项研究揭示了以下四点。首先，我们生活的环境已经被抗菌剂污染，并且浓度低于LC-MS/MS的检测限。其次，有可能抗菌剂不能在水处理厂适当地去除。第三，分离的革兰阴性杆菌对LC-MS/MS检测不到的抗菌药物具有耐药性。第四，相当一部分革兰阴性杆菌对喹诺酮类和碳青霉烯类抗生素不敏感，这些MDRO可能威胁人类健康。

This study revealed the following four points. Firstly, the environment where we live has been polluted with antimicrobials and the concentrations were less than detection limit by LC-MS/ MS. Secondly, there was possibility that antimicrobials could not appropriately removed at water-treatment plants. Thirdly, the isolated gram-negative bacilli showed resistance to antimicrobials whose concentrations were undetectable by LC-MS/ MS. Fourthly, quite a few bacilli were not sensitive to Quinolones and Carbapenems, and these MDROs might threaten human health.