Analysis on the recognition mechanisms of molecular pattern of plant pathogenic fungi and signaling network

为了阐明植物对病原菌的基本抗性机制，本研究分析了病原菌细胞表面结构的改变及其参与的识别和信号网络对植物防御反应的影响。特别是利用稻瘟菌和拟南芥。基于基因组的方法，对病原菌识别下游的信号网络--炭疽菌系统进行了广泛的分析。操纵与抗病有关的关键转录因子使我们获得了抗病转基因水稻植株。

In this research project, to elucidate plant basal resistance mechanisms against plant pathogenic fungi, modification of cell surface structure of pathogen and its involvement of recognition and signaling network leading to plant defense response was analyzed. Especially, using rice-rice blast fungus and Arabidopsis thaliana. anthracnose fungus system, signaling network downstream of pathogen recognition was extensively analyzed based on genome based approach. Manipulation of pivotal transcription factor involving disease resistance enabled us to generate disease resistant transgenic rice plants.