An experimental study for developments of a 4D-imaging system and a novel gene therapy for the hemangioma using nanobubbles and ultrasound

本研究的目的是开发一种基于纳米气泡和超声的血管瘤诊断成像系统和基因治疗系统。在本研究中，我们以实验肿瘤模型为基础，利用纳米气泡和高频超声图像分析设备开发了高分辨率诊断成像系统。此外，我们能够提出一种新的血管瘤基因治疗方法的可能性，通过转移质粒DNA，抑制肿瘤的生长，利用纳米气泡和超声波。

The aim of the present study is to develop a diagnostic imaging system and gene therapy system for hemangioma using nanobubbles and ultrasound. In the present study, by using experimental tumor model, we developed a high-resolution diagnostic imaging system utilizing nanobubbles and high-frequency ultrasound image analysis equipment. In addition, we were able to present the possibility of a new gene therapy method for hemangioma by transfer of a plasmid DNA, which inhibited the tumor growth, by utilizing nanobubbles and ultrasound.