Effect of in utero exposure to valproic acid on cerebral cortical histogenesis
Effect of in utero exposure to valproic acid on cerebral cortical histogenesis
批准号:
22791038
负责人:
SHIMOZATO Sachiko
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
丙戊酸(VPA)是一种抗癫痫药物,被认为是组蛋白去乙酰化酶(hdac)的抑制剂。本研究的目的是利用小鼠模型评价子宫内暴露于VPA对大脑皮层组织发生的影响。我们发现
英文摘要
Valproic acid (VPA), an antiepileptic drug, is known to act as an inhibitor against histone deacetylases (HDACs). A purpose of this research was to evaluate effects of in utero exposure to VPA on cerebral cortical histogenesis using mouse model. We found
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会议论文
The tailor-made medicine of clobazam based on the CYP2C19 polymorphisms.
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批准号:19790741
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$1.39万
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财政年份:2007
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负责人:SHIMOZATO Sachiko
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依托单位:
海外基金