Transport Response in mammalian young: Analysis of neuromolecular mechanism

在许多晚期哺乳动物中，母亲怀孩子。与此同时，被传送的年轻人立即采取紧凑的姿势，保持冷静。这种幼仔对母体运输的反应被称为“运输反应（TR）”。我们使用小鼠幼仔研究了TR的出生后发育和调节机制。我们发现TR是固定和姿势调节的复杂组合。触觉感觉和本体感觉是TR制动成分的必要条件。TR的姿势调节成分依赖于小脑功能。这些发现表明，TR是一种涉及多个脑区进行调节的子代特异性反应。

A mother carries the young in many altricial mammals. Meanwhile, the transported young immediately assume a compact posture and stay calm. This young's response to maternal transport is called "Transport Response (TR)". We studied the postnatal development and regulatory mechanisms of TR using mouse pups. We found that TR was an intricate combination of immobilization and postural regulation. Tactile sensation and proprioception were essential for immobilization component of TR. The postural regulation component of TR was dependent on the cerebellar function. These findings indicate that TR is a filial-specific response that involves multiple brain areas for its regulation.