Effects of probiotics in human evolutional model

用焦磷酸测序的方法对黑猩猩口腔菌群进行了分析，发现黑猩猩口腔菌群中的主要科为韦氏菌科，与人类口腔菌群不同。我们还在黑猩猩口腔中发现了一种新的变形链球菌，命名为特罗格罗链球菌，是从人和猴子体内分离的不同种类的本土链球菌。这些结果表明，对黑猩猩口腔的调查可能有助于人类的口腔健康，因为口腔菌群是随着宿主的进化而进化的。

We have been analyzing the oral flora in chimpanzee by the pyrosequencing method, and found the major family was Veillonellaceae, which was different from human oral flora. We have also found a novel mutans streptococci in chimpanzee oral cavities, and named as “Streptococcus troglodytae”, which was different kind of indigenous streptococci isolated from human and monkey. These results suggest that the investigation of chimpanzee oral cavities may contribute human oral health, because the oral flora has been evolved with the host evolution.