Mechanism of cell death and development of a new therapy against noise-induced hearing loss

我们首先制造了由强噪声引起的听力损失的动物模型。在听力损失动物模型中，我们阐明了导致内毛细胞死亡（凋亡）的机制。最后，在这些结果的基础上，我们考察了各种方法治疗听力损失的方法，并获得了听力功能/内耳形态不全的双侧听力损失可能治愈的结果。

We first manufactured the animal models that became hearing loss induced by intense noise. In the hearing loss animal model, we elucidated the mechanism which led to the cell death (apoptosis) of inner hair cells. Finally, based on these results, we examined the method that hearing loss was treated by various kinds of approaches, and the results that might cure hearing loss in the both sides where were in hearing function / inner ear morphology were obtained.