Development of a new treatment for renal ischemic-reperfusion injury using ETS-GS, a novel vitamin E

我们研究了新型维生素E衍生物ETS-GS对大鼠肾脏缺血再灌注损伤的治疗作用。在本研究中，我们发现ETS-GS改善了肾缺血再灌注后的存活率和肾功能，组织学评价也证实了这一点。此外，我们的结果提示，ETS-GS对肾脏缺血再灌注损伤的改善作用机制可能与其抗氧化作用有关。

We investigated whether ETS-GS, a novel vitamin E derivative, had therapeutic effect against renal ischemic-reperfusion injury in rat model. In this study, we found that ETS-GS improved the survival retes, renal disfunction after renal ischemic-reperfusion, which was also demonstrated by histological evaluation. In addition, our results indicated that the mechanism of improvement effect against renal ischemic-reperfusion injury may be involved in antioxidant effect by ETS-GS.