How AIDS influences on African Endemic Kaposi's sarcoma?

我们研究了流行病学的卡波西肉瘤（KS），包括三个省，西部，尼扬扎和东非大裂谷省在肯尼亚东部非洲西部的18年期间，1980年至1997年的过渡。人们普遍认为，自20世纪80年代中期以来，艾滋病流行病一直在这一地区蔓延。在比较艾滋病流行前后KS的病理学研究结果时，I . KS在所有恶性肿瘤中的频率从0.6 '/，2增加到0.8'/，。艾滋病流行后，KS男女比例由流行前的9：1变为6：1，3。艾滋病流行前KS年龄分布的两个高峰由幼儿期（5岁左右）和中年组（50岁以上）转变为艾滋病流行后的三个高峰，包括青少年年龄组（20 ~ 30岁）。AIDS流行后，成人患者中播散性和侵袭性KS伴淋巴结转移的发生率升高，6。KS在半干旱地区和热带高地的居民中迅速蔓延，在艾滋病流行之前，这些地区很少发现病人。这些结果表明，艾滋病在肯尼亚西部地区流行后，与艾滋病有关的KS数量增加，并迅速蔓延。东非。

We studied an epidemiological transition of Kaposi's sarcoma (KS), covering three provinces, Western, Nyanza and Rift Valley Provinces in the western part of Kenya East Africa during the 18-year period between 1980 and 1997. It is generally accepted that AIDS epidemics has been spreading in this area since the middle of the 1980's. When comparing the results of geopathological study on KS before and after the AIDS epidemic; I . The frequency of KS among all malignant tumors has increased to 0.8'/, from 0.6'/, , 2. The male to female ratio of KS has shifted to 6:1 after AIDS epidemic from 9:1 before AIDS epidemic, 3. Two peaks of the age distribution of KS in the early childhood (around 5 years old) and the middle age group (over 50 years old) before AIDS epidemic have changed to three peaks, including the adolescent age group (20 - 30 years old) after AIDS epidemic, 4 The mean age of the KS patients has shifted to 36 years old after AIDS epidemic from 40 years old before AIDS epidemic, 5. The frequency of disseminated and aggressive form of KS with lymph node involvement among the adult patients has elevated after AIDS epidemic, 6. KS is rapidly spreading among the inhabitants in semi-arid areas and tropical highlands, where very few patients were found before AIDS epidemic. These findings suggest that AIDS-related KS has been increasing in number and spreading rapidly after AIDS epidemic in western part of Kenya. East Africa.