Microbiology Whole Genome Sequencing

密苏里州卫生和高级服务部 国家公共卫生实验室 FOA PAR-20-105项目摘要 实验室灵活资助模式 学科A(微生物学)：轨道4全基因组测序 目的： 密苏里州卫生和高级服务部(DHSS)州立公共卫生实验室 (MSPHL)寻求FDA合作协议资助机会，以增强基因组Trakr 通过捕获当前和不断演变的非临床病原体的基因组多样性来实现网络 在FDA相关领域。 这项合作协议的目标和成果包括： 1.MSPHL将对多种沙门氏菌、单核细胞增多性李斯特菌、志贺氏菌毒素进行测序 产生大肠杆菌和其他食源性相关生物。 2.MSPHL将把产生的数据上传到国家生物技术中心 研究人员和公共卫生官员可以真正获取的信息- 时间对比与分析。 3.实时比较和分析有助于减少解决问题所需的时间 食源性疾病暴发调查，减少食源性疾病和死亡。 第1页，共1页

Missouri Department of Health and Senior Services State Public Health Laboratory Project Abstract for FOA PAR-20-105 Laboratory Flexible Funding Model Discipline A (Microbiology): Track 4 Whole Genome Sequencing Purpose: The Missouri Department of Health and Senior Services (DHSS) State Public Health Laboratory (MSPHL) seeks FDA cooperative agreement funding opportunity to enhance the Genome Trakr network by capturing the current and evolving genomic diversity of non-clinical pathogens across FDA relevant areas. The goals and outcomes of this cooperative agreement include the following: 1. The MSPHL will sequence a variety of Salmonella, Listeria monocytogenes, Shiga-toxin producing E. coli and other foodborne related organisms. 2. The MSPHL will upload the data generated to the National Center for Biotechnology Information which can be accessed by researchers and public health officials for real- time comparison and analysis. 3. The real time comparison and analysis will aid and reduce the time needed to solve foodborne illness outbreak investigations and reduce foodborne illnesses and deaths. Page 1 of 1