Mentoring and Patient-Oriented Research in Mind-Body Exercise

这项职业生涯中期研究人员奖(K24)提案将支持Gloria Yeh博士以患者为导向的研究和 指导综合医学领域的实习生。在过去的16年里，叶博士开发了一种 以生活方式和冥想锻炼为重点的中西医结合研究成功方案 心血管和肺部疾病的干预措施。叶博士的研究项目设在贝斯大学 哈佛医学院以色列女执事医学中心，她在那里担任心身主任 美国国立卫生研究院国家补充与综合研究中心主任 健康(NIH NCCIH)资助的T32奖学金(哈佛医学院综合研究奖学金 医学)。叶博士目前的研究计划包括两项NCCIH R01拨款，她担任这两项拨款的 首席研究员，以及她担任主要合作者的其他几项研究。这份K24提案 概述职业发展计划，以提高她的研究计划和质量/数量 辅导，包括参加领导力和辅导培训，额外的课程作业(高级 生物统计、混合方法和与研究内容有关的培训)，并定期与 资深教职顾问。整个计划的目标突出了代表当前形势的三个中心主题 研究和未来扩展的领域：1)进行严格的研究，评估临床疗效和 心身疗法在心血管和肺部疾病及其他慢性疾病中的作用机制； 2)应用创新的方法，更好地了解个人的积极组成部分的贡献 多模式行为、心身方法；以及3)调查患者因素的复杂阵列 影响参与和坚持健康的生活方式，特别是锻炼，以及如何以身心为目标 治疗可以增强/支持这一点。有了K24提供的保护时间，叶博士计划推进 她在这些领域的研究，并为导师提供了一个多样化、创造性和支持性的研究环境 对初级调查人员进行综合医学方面的培训。

This Midcareer Investigator Award (K24) proposal will support Dr. Gloria Yeh in patient-oriented research and mentoring of trainees in the field of integrative medicine. Over the past 16 years, Dr. Yeh has developed a successful program of integrative medicine research with focus on lifestyle and meditative exercise interventions for cardiovascular and pulmonary conditions. Dr. Yeh's research program is based at the Beth Israel Deaconess Medical Center at Harvard Medical School, where she serves as Director of Mind-Body Research, Director of the National Institutes of Health National Center for Complementary and Integrative Health (NIH NCCIH) funded T32 fellowship (Harvard Medical School Research Fellowship in Integrative Medicine). Dr. Yeh's current research program includes two NCCIH R01 grants for which she serve as a principal investigator, and several other studies for which she serves as a key collaborator. This K24 proposal outlines career development initiatives for enhancing her research program and the quality/quantity of mentoring including participation in leadership and mentoring training, additional coursework (in advanced biostatistics, mixed methods, and research content-related trainings), and regular meetings with established senior faculty advisors. The overall Program Aims highlight three central themes which represent current research and areas of future expansion:1) To conduct rigorous research evaluating the clinical efficacy and mechanisms of mind-body therapies in cardiovascular and pulmonary disease and other chronic conditions; 2)To apply innovative methodology to better understand the contributions of individual, active components of multimodal behavioral, mind-body approaches; and 3) To investigate the complex array of patient factors that impact engagement and adherence to healthy lifestyle, particularly exercise, and how targeted mind-body therapies can augment/support this. With the protected time afforded by this K24, Dr. Yeh plans to advance her research in these areas and provide a diverse, creative, and supportive research environment to mentor and train junior investigators in integrative medicine.