Learning, Memory, and Plasticity (LaMP) Training Program

项目概要/摘要。 这是一个新的应用程序，以支持先进的博士前培训学习，记忆和可塑性（LaMP） 在加州大学戴维斯分校加州大学戴维斯分校的LaMP研究既广泛又深入，跨越4所学校和学院， 研究的主要层次-认知、系统、细胞/分子和疾病。31名教练高度重视 合作和价值的跨学科方法，他们的研究。我们设计了一个创新的 培养下一代神经科学家的计划，以弥合LaMP主要水平之间的差距 研究-认知，系统，细胞/分子-以促进我们对LaMP疾病的理解 减轻他们给家庭，社会和公众健康带来的巨大负担。我们的计划旨在支持 每年6名高级博士前培训生，这是创建一个跨越传统的团队所必需的规模。 学科边界，跨越分析层次，并解决基础和转化研究。 来自6个参与研究生团体的学员将有资格申请第二年的LaMP培训计划 (and第三年，在特殊情况下），他们的研究生培训。2年培训计划 方案有6个组成部分。(1)学员将在至少一个LaMP教师实验室进行研究，并将 由来自LaMP研究不同领域的另一位培训师共同指导。(2)学员将接触到 在LaMP的每个领域的基本和新兴的概念，通过一个2季度的核心课程，包括 互动讲座以及基于实验室的沉浸式教学，为学员提供了解利弊的工具 每个层次的分析所使用的概念和方法。(3)学员也将接触到LaMP 通过由教学和访谈/视频会议组成的课程，涵盖临床，认知， 每种疾病的系统和分子方面。(4)学员将接受有针对性的职业发展培训 通过每隔一周与项目培训师举行一次会议，强调关键和跨学科 思维，演讲技巧，学术界以外的研究相关职业的正式讨论，以及紧迫的 该领域的问题，如数据分析，道德，严谨性和可重复性。(5)学员将获得 在补助金写作的广泛培训，其次是一个模拟研究部分之前，他们的NRSA提交的 第二年融资的第一季度。(6)学员将参加年度计划务虚会， 参加一个受邀的LaMP演讲者系列。通过这些元素，这个新的培训计划将产生一个新的 一代真正跨层次和跨尺度思考的科学家，他们拥有技能、动力和动力， 合作解决学习、记忆和可塑性方面最重要的问题， 改善人类健康。

Project Summary/Abstract. This is a new application to support advanced predoctoral training in Learning, Memory, and Plasticity (LaMP) at UC Davis. LaMP research at UC Davis is both broad and deep, spanning 4 schools and colleges and all of the major levels of research—cognitive, systems, cellular/molecular, and disease. The 31 Trainers are highly collaborative and value interdisciplinary approaches to their research. We have designed an innovative Program to train the next generation of neuroscientists to bridge the gaps between the major levels of LaMP research—cognitive, systems, cellular/molecular—in order to promote our understanding of LaMP disorders and reduce their tremendous burden on families, society, and public health. Our program proposes to support 6 advanced predoctoral Trainees per year, a size essential for creating a group that crosses traditional disciplinary boundaries, spans levels of analysis, and addresses both basic and translational research. Trainees from 6 participating graduate groups will be eligible to apply to the LaMP Training Program in Year 2 (and Year 3, under exceptional circumstances) of their graduate training. The proposed 2-year Training Program has 6 components. (1) Trainees will conduct research in at least one of the LaMP faculty labs and will be co-mentored by another trainer from a distinct area of LaMP research. (2) Trainees will be exposed to the essential and emerging concepts in each of the fields of LaMP through a 2-quarter core course consisting of interactive lectures as well as lab-based immersion to give trainees the tools to understand the pros and cons of both the concepts and methods used at each level of analysis. (3) Trainees will also be exposed to LaMP disorders through a course consisting of didactic and interview/video sessions that span clinical, cognitive, systems and molecular aspects of each disease. (4) Trainees will receive targeted career development training through a meeting every other week with Program Trainers—emphasizing critical and cross-disciplinary thinking, presentation skills, formal discussion of research-related careers outside of academia, and pressing issues in the field such as data analysis, ethics, and rigor and reproducibility. (5) Trainees will receive extensive training in grant writing, followed by a mock study section prior to submission of their NRSA in the first quarter of their second year of funding. (6) Trainees will participate in an annual program retreat and attend an invited LaMP speaker series. Through these elements, this new Training Program will produce a new generation of scientists who truly think across levels and scales and who have the skills, drive, and motivation to work collaboratively to tackle the most important issues in learning, memory, and plasticity in order to improve human health.