Health and Retirement Study: Harmonized Cognitive Assessment Protocol (HCAP)

项目摘要/摘要 健康和退休研究(HRS)合作协议的主要目标是收集和 分发多学科数据以支持老龄化研究。认知障碍和痴呆症，包括 阿尔茨海默病和阿尔茨海默病相关痴呆(AD/ADRD)，给 家庭和政府政策。为研究界提供新的和更丰富的数据，以研究 认知损害和痴呆的患病率、预测因素和结果，我们进行了HRS HRS 2016外地期间的统一认知评估议定书(HCAP)研究，其中我们 对随机选择的约3,200人进行了1小时的家庭认知测试 65岁以上的全国有代表性的HRS受访者，以及20分钟的线人访谈。在 拟议的HCAP 2020后续研究，我们将重新进行相同的HCAP居家认知评估 和举报人向原始HCAP样本(n~2,250)的所有幸存成员报告，并向新的随机 2020年65岁至68岁人群样本(n~720)。HCAP 2020后续研究将提供广泛的新的 更好地评估美国老年人认知能力下降轨迹的数据，包括新的 认知障碍和痴呆症。这些数据也将提供前所未有的机会，以更好地 了解美国和世界各地痴呆症的发病率和流行率的趋势。

PROJECT SUMMARY/ABSTRACT The primary aim of the Health and Retirement Study (HRS) cooperative agreement is to collect and distribute multi-disciplinary data to support research on aging. Cognitive impairment and dementia, including Alzheimer's disease and Alzheimer's disease related dementias (AD/ADRD), impose enormous burdens on families and government policies. To provide the research community with new and richer data to study the prevalence, predictors, and outcomes of cognitive impairment and dementia, we undertook the HRS Harmonized Cognitive Assessment Protocol (HCAP) Study during the HRS 2016 field period, in which we administered a supplemental in-home 1-hour battery of cognitive tests to about 3,200 randomly selected and nationally representative HRS respondents aged 65+, as well as a 20-minute informant interview. In the proposed HCAP 2020 follow-up study, we will re-administer the same HCAP in-home cognitive assessment and informant report to all surviving members of the original HCAP sample (n ~ 2,250), and to a new random sample of those aged 65 to 68 in 2020 (n ~ 720). The HCAP 2020 follow-up study will provide extensive new data to better assess trajectories of cognitive decline among older US adults, including the incidence of new cognitive impairment and dementia. These data will also provide an unprecedented opportunity to better understand trends in the incidence and prevalence of dementia in the US and around the world.