PDX Trial Center for Breast Cancer Therapy

项目摘要 积极的试点项目计划是新想法的宝贵来源，可以带来新的模式， 技术中心。同样，PDXNet中其他中心之间的互动和活动也将 通过利用其他机构的专业知识和能力来充实每个中心。试点项目的目标 和跨网络活动核心是： 1.资助PDTC内的创新试验项目，以开发新技术或探索创新的新技术。 与母项目相关的方法。 2.资助trans-PDXNet合作项目，以增强每个中心和网络的影响力。 3.资助PDTC和非PDXNet调查人员在一个新领域的合作项目， 实现中心的目标。 我们已经制定了一种方法，在每年的一次会议上征求PDTC内部和非PDXNet试点项目的申请。 基础和审查申请使用一个深思熟虑的结构委员会，包括在中心的关键专业知识 并利用PDTC咨询委员会。审查申请的主要标准将包括创新， 重要性，概念和科学严谨性，进一步实现PDTC目标的潜力，以及 未来的外部融资。我们还将根据以下建议资助跨PDXNet合作项目： PDXNet指导委员会

Project Summary Active pilot project programs are an invaluable source of new ideas, and can serve to bring novel models and technologies to a Center. Similarly, interactions and activities between other Centers in the PDXNet will also enrich each Center by leveraging expertise and capabilities at other institutions. The goals of the Pilot Projects and Trans-Network Activities Core are: 1. To fund innovative pilot projects within the PDTC to develop new technologies or explore innovative new approaches related to the parent projects. 2. To fund trans-PDXNet collaborative projects to enhance the impact of each Center and of the network. 3. To fund collaborative projects between the PDTC and non-PDXNet investigators in a novel area related to the advancement of the Center’s goals. We have developed an approach to solicit Intra-PDTC and non-PDXNet pilot project applications on an annual basis and review applications using a thoughtfully structured committee comprising key expertise in the Center and utilizing the PDTC Advisory Boards. Major criteria for review of applications will include innovation, significance, conceptual and scientific rigor, the potential to further the goals of the PDTC, and the potential for future external funding. We will also fund Cross-PDXNet collaborative projects based on recommendations from the PDXNet Steering Committee.