Cellular and Molecular Biology at Michigan

项目摘要/摘要： 细胞和分子生物学(CMB)博士项目成立于大约40年前， 协调学生在广泛的细胞和分子生物学领域的跨部门培训。招商银行享有 来自拉克姆研究生院和医学院以及 教职部。项目学院在科学上是多样化的，并且资金充足。培训机会范围 来自大量领域的基础研究(结构生物学、生物化学、遗传学、分子生物学、 细胞生物学、发育、生理学和神经科学)，到更多的翻译主题(癌症、新陈代谢 疾病、免疫学、神经退化、衰老、微生物发病机制和干细胞生物学)。尽管 学生的个人论文项目是集中的，该计划提供了对整个范围的暴露 CMB研究通过每周学生研讨会(CMB 850)，学生组织的短期课程，年度 研讨会/海报会议和年度务虚会。因此，该计划吸引了以下学生和教职员工 将受益于广泛接触广泛的研究，这是我们日益合作的不可或缺的 科学环境。该计划从全国范围内吸引了一批优秀和多样化的学生。 约75%的人参加了生物医学科学(PIBS)项目，这是14岁以下学生的入学保护伞 生物医学博士计划)，约25%来自医学科学家培训计划(MSTP)。这个 课程，通常由PIBS/CMB学生在第二年年中完成，由MSTP/CMB完成 学生在第一阶段结束时，是灵活的，但涵盖了生物化学、遗传学和细胞的核心领域 生物学以及包括定量训练在内的选修课程。候选人资格在以下情况下获得 在第二年完成一项资格考试，其依据的是以学生的预期为中心的建议 研究。CMB学生在竞争外部奖学金方面非常成功(NIH NRSA，NSF)和 参与支持科学推广和多样性的活动。目前有62名学生在 程序。在过去的5年里，74名学生参加了该项目，72名学生获得了博士学位。这个 平均获得学位的时间约为5.6年，学生平均发表2篇第一作者论文， 总计4.2美元。招商银行博士毕业生继续从事学术研究和教学，并在#年从事商业研究 制药业、生物技术和政府实验室，以及各种非研究但科学- 相关职业。作为竞争续订申请的NIGMS T32培训补助金提供了 资源。大多数PIBS/CMB学生在二年级得到培训补助金的支持，一些学生在 他们的第三个；MSTP/CMB学生有资格在他们的G2年。无论是否得到赠款的支持，所有 中巴学生也有同样的要求。在本申请中，我们每年申请16个名额，第二年申请8个名额 学生和8名三年级学生(或二年级MSTP学生)。这比获奖名额增加了1个名额。 上一个周期(15个，被自动减支削减到14个)。

Project Summary/Abstract: The Cellular and Molecular Biology (CMB) Ph.D. Program was founded approximately forty years ago to coordinate interdepartmental training of students in broad areas of cellular and molecular biology. CMB enjoys strong institutional support from Rackham Graduate School and the Medical School as well as from the faculty's departments. Program Faculty are scientifically diverse and well-funded. Training opportunities range from basic research in a large number of areas (structural biology, biochemistry, genetics, molecular biology, cellular biology, development, physiology and neuroscience), to more translational topics (cancer, metabolic disease, immunology, neuro-degeneration, aging, microbial pathogenesis and stem cell biology). Though students' individual dissertation projects are focused, the Program provides exposure to the entire spectrum of CMB research through the weekly student seminar (CMB 850), student-organized short courses, an Annual Symposium/Poster Session and an Annual Retreat. Thus, the Program appeals to students and faculty who will benefit from broad exposure to a wide range of research, indispensible in our increasingly collaborative scientific environment. The Program draws an outstanding and diverse group of students from a national pool. Approximately 75% join from the Program in Biomedical Sciences (PIBS, an umbrella for admission to 14 biomedical Ph.D. programs) and about 25% from the Medical Scientist Training Program (MSTP). The curriculum, typically completed by PIBS/CMB students by the middle of the second year and by MSTP/CMB students by the end of the first, is flexible, yet encompasses core areas of biochemistry, genetics and cell biology as well as elective coursework that includes quantitative training. Candidacy is achieved after completion of a qualifying exam in the second year based on a proposal that centers on the student's intended research. CMB students are highly successful at competing for external fellowships (NIH NRSA, NSF) and participate in activities that support scientific outreach and diversity. There are currently 62 students in the program. During the past 5 years, 74 students joined the program and 72 students received Ph.D.s. The average time to degree is approximately 5.6 years, with students publishing, on average, 2 first-author papers, 4.2 total. CMB Ph.D. graduates go on to careers in academic research and teaching, in commercial research in the pharmaceutical industry, biotech and government laboratories, as well in diverse non-research but science- related careers. The NIGMS T32 Training grant for which this is a competing renewal application provides key resources. Most PIBS/CMB students are supported by the training grant in their second year and some are in their third; MSTP/CMB students are eligible during their G2 year. Whether supported by the grant or not, all CMB students have the same requirements. In this application, we request 16 slots per year, 8 for 2nd year students and 8 for 3rd year (or G2 year MSTP students). This is an increase of 1 slot from what was awarded last cycle (15, cut to 14 by the sequester).