Training Program in Substance Use Disorders

摘要 西奈山伊坎医学院(ISMMS)药物使用障碍培训计划 将为后期博士后(PhD)学生和早期博士后研究员提供 物质使用障碍(SODS)研究方面的培训，利用细胞、 分子和行为神经科学、翻译神经科学、神经学、精神病学、基因组科学 以及ISMMS的药理科学。该计划的首要目标是提供严格、广泛的- 基于多学科的个性化培训，提供更多的指导、协作、 和职业发展，旨在为SODS的下一代独立调查人员做好准备 研究。这一新培训计划的核心将是一支卓越的培训教师队伍，代表卓越的 基础和临床相关主题的多样性；从突触可塑性和染色质重塑；认知， 社交和情绪障碍；情绪、动机和焦虑障碍；成瘾；人类 神经心理学和认知神经科学--所有这些都与肥皂泡有关。培训计划包括以下内容： 相关部分：学术课程、实验室培训、非课程培训活动(研讨会、 务虚会等)、测试/评估、教学机会、指导和职业发展活动。这个 ISMMS多样化的研究环境将为实验室在核心优势领域提供机会， 包括翻译神经科学，计算神经科学，神经精神病学基因组学， 神经成像、表观遗传学、突触和行为可塑性，以及对不同模型系统的研究。 培训计划包括十多项新创建或改编的倡议 支持多学科协作培训的现有项目，以及 促进非凡的严谨和创造力。博士后和博士后实习生将参加必修和 可选的培训活动，以确保在基础神经科学方面打下坚实的基础，并提供学习和 与来自ISMMS的同行和教职员工，包括那些在生物医学科学研究生院的人， 医学院、跨学科中心和研究所，以及弗里德曼脑研究所。创建结构化的 在学员的整个职业生涯中进行指导的文化是培训计划的一个显著特点。 正式和非正式的咨询和辅导将纳入跨角色和不同级别的培训，包括 为培训教师和赞助商(教师)提供指导机会。整合博士后和博士后 通过正式机制进行的培训将在总体培训体验中提供更大的连续性， 有兴趣从事SODS研究的受训者之间的合作机会，并将受益 ISMMS的神经科学研究工作。药物使用障碍培训计划将为 最有前途的受训人员，在所有级别的SUD研究中从事富有成效的独立职业-从临床前到 遗传学，细胞和分子机制的疾病，临床研究和干预。

SUMMARY The Training Program in Substance Use Disorders at the Icahn School of Medicine at Mount Sinai (ISMMS) will offer late-stage predoctoral (PhD) students and early-stage postdoctoral fellows an integrated program of training in substance use disorders (SUDs) research that leverages the exceptional expertise in cellular, molecular and behavioral neuroscience, translational neuroscience, neurology, psychiatry, genomic science and pharmacological sciences at ISMMS. The overarching goal of the program is to provide rigorous, broad- based, individualized, and multidisciplinary training with enhanced opportunities for mentoring, collaboration, and career development designed to prepare the next generation of independent investigators in SUDs research. At the heart of this new Training Program will be a superb training faculty representing remarkable diversity in basic and clinically relevant topics; from synaptic plasticity and chromatin remodeling; cognitive, social, and emotional disorders; disorders of mood, motivation, and anxiety; addiction; human neuropsychology; and cognitive neuroscience – all relevant to SUDs. The Training Program comprises inter- related components: academic coursework, laboratory training, non-curricular training activities (seminars, retreats, etc.), testing/evaluation, teaching opportunities, mentoring, and career development activities. The diverse research environment at ISMMS will provide for laboratory opportunities in core areas of strength, including in translational neuroscience, computational neuroscience, neuropsychiatric genomics, neuroimaging, epigenetics, and synaptic and behavioral plasticity, and the study of diverse model systems. The Training Program includes more than a dozen initiatives that have been newly created or adapted from existing programs to support training in SUDs, which emphasize multidisciplinary collaborations, and the promotion of exceptional rigor and creativity. Pre- and post-doctoral trainees will participate in required and optional training activities to ensure strong grounding in basic neuroscience and opportunities to learn from and with peers and faculty from across ISMMS, including those in the Graduate School of Biomedical Sciences, the medical school, interdisciplinary Centers and Institutes, and the Friedman Brain Institute. Creating a structured culture of mentoring across the career continuum of participants is a hallmark feature of the Training Program. Formal and informal advising and mentoring will be integrated into training across roles and levels, including mentoring opportunities for training faculty and sponsors (preceptors). Integrating predoctoral and postdoctoral training through formal mechanisms will provide greater continuity in the overall training experience, enhanced opportunities for collaboration among trainees interested in pursuing careers in SUDs research, and will benefit the neuroscience research effort at ISMMS. The Training Program in Substance Use Disorders will prepare the most promising trainees for productive, independent careers in SUD research at all levels – from preclinical genetics, cellular and molecular mechanisms of the disorders, to clinical research and interventions.