Animal Behavior Core

项目概要-动物行为核心 动物行为核心（ABC）为研究人员提供了一个基础设施， 在啮齿动物模型中进行先进和创新的功能评估，以帮助了解起源和 治疗智力和发育残疾。澳大利亚广播公司支持旨在发展 以及表征由基因鉴定或基因修饰研究产生的新型IDD啮齿动物模型 或IDDRC研究附属机构进行的环境暴露研究。此外，ABC至关重要， IDDRC研究人员评估内在（基于基因）和/或外在（手术， 环境、化学或基于药物的）干预。ABC的具体目标是：1。提供科学的， 为使用IDD研究动物模型的研究附属机构提供管理和预算服务; 2.为研究人员提供行为测试设备、研究空间和新颖的测试方案， 能够对IDD啮齿动物模型中的行为进行最先进的评估; 3.培训研究附属机构及其 工作人员在适当的测试协议; 4.协调其他IDDRC核心和支持服务 临床应用开发; 5.促进开发更多的创新技术， 可以与IDD啮齿动物模型中行为功能的评估结合使用。

PROJECT SUMMARY – ANIMAL BEHAVIOR CORE The Animal Behavior Core (ABC) provides an infrastructure for investigators to perform the most advanced and innovative functional assessments in rodent models to assist in understanding the origins and treatment of intellectual and developmental disabilities (IDD). The ABC supports efforts aimed at developing and characterizing novel rodent models of IDD that result from gene identification or gene modification research or environmental exposure studies performed by IDDRC Research Affiliates. Furthermore, the ABC is critical as IDDRC investigators evaluate the functional outcomes of intrinsic (gene-based) and/or extrinsic (surgical, environmental, chemical, or drug-based) interventions. Specific Aims of the ABC are: 1. Provide scientific, management, and budgeting services to Research Affiliates using animal models for studies of IDD; 2. Provide behavioral testing equipment, research space, and novel testing protocols for investigators that enable state-of-the-art assessment of behavior in rodent models of IDD; 3. Train Research Affiliates and their staff in appropriate testing protocols; 4. Coordinate services across other IDDRC Cores and support development of clinical applications; and 5. Promote the development of additional innovative techniques that can be utilized in conjunction with assessments of behavioral functions in rodent models of IDD.