Predoctoral Training Program in Chemistry and Biology

项目摘要/摘要 由于主要的技术和概念，生物医学研究的格局正在迅速变化 进步，创造新的研究机会和扩大职业范围，同时摆姿势 定量和多学科科学研究生培训面临的挑战。此外，强调 在社会经济转型中，研究生教育和导师制的最佳实践应运而生。对…作出回应 这些持续的发展以及学生和更广泛的社会的需求， 生物化学与分子生物学(BMB)和加州大学化学系(CHEM) 芝加哥大学提出了一个跨学科的博士前培训计划，该计划针对的是化学和化学之间的接口 生物科学(CBI)，旨在招募、教育和培训多样化的新一代生物医学人才 通过在培训、指导和教育方面部署新的最佳实践来促进严格的交叉 在发展量化素养的同时进行学科研究，保持核心学科的深度，从而 为他们在需要科学培训的职业生涯中取得成功做好准备。该计划受益于杰出的 教师和学生以及跨学科科学新课程的介绍。25名培训教职员工 由12名BMB聘任教员(1名联合聘任化学教员)、10名教员组成 化学(一个在BMB有联合任命)，两个在本·梅癌症研究部，以及 一个是分子工程学。发展跨学科培训的战略包括：(1)令人满意 完成了化学生物学的核心课程和其他科学系的广泛课程 学科；(2)跨学科论文研究；(3)全程参加一系列月度会议 被定为“化学与生物交界的综合讨论”的学年 熟悉理论概念和方法；(4)参加两次季度会议，重点是 生物中的高级化学工具(ACT-Bio)和需要化学解决方案的生物学问题 (5)参加两次为期半天的年度活动：一个小型研讨会和一个“内部”海报 务虚会；以及(6)举办讲习班，以促进量化扫盲以及严谨和可再现性。参与一项 整个部门的职业发展计划帮助学生探索并为不同的职业道路做准备。 通过合作加强了教师跨学科研究的广泛兴趣 研究和教学确保了有意义的交叉培训的广泛机会。该计划将 通过更频繁的建议、指导契约和要求的年度指导来促进卓越的指导 教师导师制培训。通过积极参与管道、外展和桥梁项目，以及 通过参与研究生招生和教师招聘，项目教师将促进 招募和留住日益多样化的科学界。一个外部咨询委员会和 专业实施的评价工具将指导改进该方案。

PROJECT SUMMARY/ABSTRACT The landscape of biomedical research is changing rapidly due to major technological and conceptual advances, creating new research opportunities and expansion in the scope of occupations while posing challenges for graduate training in quantitative and multidisciplinary science. Furthermore, an emphasis on best practices in graduate education and mentorship has emerged from socioeconomic shifts. To respond to these ongoing developments and the needs of students and the broader society, the Department of Biochemistry & Molecular Biology (BMB) and the Department of Chemistry (Chem) at The University of Chicago propose an interdisciplinary, predoctoral training program directed at the interface of the chemical and biological sciences (CBI) that aims to recruit, educate and train a diverse, new generation of biomedical scholars by deploying new best practices in training, mentoring, and education to promote rigorous cross- disciplinary research while developing quantitative literacy and maintaining depth in the core discipline, thereby preparing them for success in careers that require scientific training. The program benefits from outstanding faculty and students and introduction of new courses in interdisciplinary science. The 25 training faculty consists of twelve faculty with appointments in BMB (one with a joint appointment in Chemistry), ten faculty in Chemistry (one with a joint appointment in BMB), two in the Ben May Department for Cancer Research, and one in Molecular Engineering. Strategies to develop cross-disciplinary training include: (1) satisfactory completion of a core course in Chemical Biology and a breadth course in the department of the other scientific discipline; (2) cross-disciplinary thesis research; (3) participation in a series of monthly meetings throughout the academic year designated as "Integrative Discussions at the Interface of Chemistry & Biology" to gain acquaintance with theoretical concepts and methods; (4) participation in two quarterly meetings focused on advanced chemical tools in biology (ACT-Bio) and biological problems that require chemical solutions (BPRCS); (5) participation in two in two annual half-day events: a CBI Minisymposium and an “in-house” poster retreat; and (6) workshops to promote quantitative literacy and rigor and reproducibility. Participation in a division-wide career development program helps students explore and prepare for different career paths. The broad scope of the interdisciplinary research interests of the faculty strengthened through collaborative research and teaching ensures a wide variety of opportunities for meaningful cross-training. The program will promote excellence in mentorship through more frequent advising, mentoring compacts and required annual faculty mentorship training. Through active participation in pipeline, outreach, and bridge programs, and through participation in graduate admissions and faculty recruitment, program faculty will promote the recruitment and retention of an increasingly diverse scientific community. An external advisory committee and professionally implemented evaluation instruments will guide improvements to the program.