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REPOSITORY PULL FOR UPSTATE KIDS 2020

REPOSITORY PULL FOR UPSTATE KIDS 2020
2020 年 UPSTATE KIDS 存储库拉取
批准号:
10360407
负责人:
OGUZ MANDACI
金额:
$0.11万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2020
资助国家:
美国
项目状态:
已结题
起止时间:
2020-07-22 至 2023-07-21

项目摘要

项目成果

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中文摘要
翻译
Upstate KIDS心血管疾病随访研究的目的是确定不孕症治疗是否与心血管疾病风险或青春期时间有关。研究表明,体外受精受孕后,一些青春期标志物出现改变,早期肾上腺素升高本身可能增加心血管疾病的风险。表观遗传学可能是影响治疗效果的机制。北州儿童研究包括接受不孕症治疗的儿童和自然受孕的儿童。在这项后续研究中,从6至8岁的儿童身上采集了包括血液和唾液在内的样本。还从母亲身上采血,以评估母亲心血管疾病风险的混杂性。
英文摘要
The purpose of the Upstate KIDS CVD Follow-up study is to determine if infertility treatment is associated with a risk cardiovascular disease or the timing of puberty. Studies have shown that some pubertal markers appear altered after IVF conception and early adrenarche may itself confer a risk of cardiovascular disease. Epigenetics may be the mechanism underlying treatment effects. The Upstate KIDS study consisted of children conceived by infertility treatment and children conceived naturally. In this follow-up study, specimens including blood and saliva were taken from children between the ages of 6 and 8. Blood was also taken from mothers to assess confounding by maternal CVD risk.
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REPOSITORY SERVICES FOR THE MATERNAL AND PEDIATRIC INFECTIOUS DISEASE BRANCH (MPIDB)SPECIMENS
  • 批准号:
    10404897
  • 项目类别:
  • 资助金额:
    $44.33万
  • 财政年份:
    2021
  • 负责人:
    OGUZ MANDACI
  • 依托单位:
REPOSITORY SERVICES FOR THE MATERNAL AND PEDIATRIC INFECTIOUS DISEASE BRANCH (MPIDB) SPECIMENS
  • 批准号:
    10624174
  • 项目类别:
  • 资助金额:
    $49.54万
  • 财政年份:
    2021
  • 负责人:
    OGUZ MANDACI
  • 依托单位:
REPOSITORY SERVICES FOR THE MATERNAL AND PEDIATRIC INFECTIOUS DISEASE BRANCH (MPIDB) SPECIMENS
  • 批准号:
    10838345
  • 项目类别:
  • 资助金额:
    $47.48万
  • 财政年份:
    2021
  • 负责人:
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STORAGE OF NUMOM2B FETAL DNA ALIQUOTS FROM CORD BLOOD FOR THE PREGNANCY AND PERINATOLOGY BRANCH OF NICHD
  • 批准号:
    10268324
  • 项目类别:
  • 资助金额:
    $12.86万
  • 财政年份:
    2020
  • 负责人:
    OGUZ MANDACI
  • 依托单位:
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